Brewer J B, Zhao Z, Desmond J E, Glover G H, Gabrieli J D
Neuroscience Program and School of Medicine, Stanford University, Stanford, CA 94305, USA.
Science. 1998 Aug 21;281(5380):1185-7. doi: 10.1126/science.281.5380.1185.
Experiences are remembered or forgotten, but the neural determinants for the mnemonic fate of experience are unknown. Event-related functional magnetic resonance imaging was used to identify specific brain activations that differentiated between visual experiences that were later remembered well, remembered less well, or forgotten. During scanning of medial temporal lobe and frontal lobe regions, subjects viewed complex, color photographs. Subjects later received a test of memory for the photographs. The magnitudes of focal activations in right prefrontal cortex and in bilateral parahippocampal cortex predicted which photographs were later remembered well, remembered less well, or forgotten.
经历会被记住或遗忘，但其记忆命运的神经决定因素尚不清楚。事件相关功能磁共振成像被用于识别特定的大脑激活，这些激活区分了后来被清晰记住、记忆不太清晰或被遗忘的视觉体验。在内侧颞叶和额叶区域扫描期间，受试者观看复杂的彩色照片。受试者随后接受了对这些照片的记忆测试。右侧前额叶皮层和双侧海马旁回皮层的局灶性激活程度预测了哪些照片后来被清晰记住、记忆不太清晰或被遗忘。
