Caralis D G, Varghese P J
Br Heart J. 1976 Sep;38(9):951-6. doi: 10.1136/hrt.38.9.951.
Clinical and electrophysiological studies of a 13-year-old boy with sinus bradycardia revealed sinus node dysfunction. Long-term follow-up data of members of his family indicated familial sinus node dysfucntion. Increased vagal tone was present in all patients. It is suggested that excessive vagal discharge for a pronlonged time may be the basic mechanism of sinus node dysfunction in these patients.
对一名患有窦性心动过缓的13岁男孩进行的临床和电生理研究显示存在窦房结功能障碍。对其家庭成员的长期随访数据表明存在家族性窦房结功能障碍。所有患者均存在迷走神经张力增加。提示长时间的迷走神经放电过度可能是这些患者窦房结功能障碍的基本机制。