5%的二甲基亚砜足以保存源自脐带血的干细胞。
5% Me2SO is sufficient to preserve stem cells derived from cord blood.
作者信息
Richter E, Eichler H, Raske D, Leveringhaus A, Zieger W, Kerowgan M, Goldmann S F
机构信息
German Red Cross, Blood Center Mannheim and Medical Faculty Mannheim, Germany.
出版信息
Bone Marrow Transplant. 1998 Jul;22 Suppl 1:S16.
PMID:9715875
Abstract
On the basis of historical findings, 10% dimethylsulfoxide is still used to cryopreserve stem cells. We studied a final concentration of 5% dimethylsulfoxide in cryopreservation of cord blood-derived stem cells in autologous plasma. In our opinion, a final concentration of 5% dimethylsulfoxide in autologous plasma without further additives is sufficient for cryopreservation of cord blood stem cells in a banking routine.
摘要
基于既往研究结果，10%的二甲基亚砜仍用于冷冻保存干细胞。我们研究了在自体血浆中冷冻保存脐带血来源干细胞时二甲基亚砜的终浓度为5%的情况。我们认为，在无其他添加剂的自体血浆中二甲基亚砜终浓度为5%足以在库存储存流程中冷冻保存脐带血干细胞。
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