Galus M, Schiffman R, Olkowska D
Pennsylvania Hopital, Philadephia, USA.
Liver. 1998 Jun;18(3):205-7. doi: 10.1111/j.1600-0676.1998.tb00151.x.
In North America, massive liver necrosis is due mainly to viral infection or exposure to hepatotoxins. We report an unusual case of massive liver necrosis due to diffuse liver infiltration by small cell carcinoma of the lung. The unusual presentation included hyperamylasemia due to ectopic amylase production by the tumor. In this era of liver transplantation it is important to consider malignancy in the differential diagnosis of fulminant or acute liver failure prior to liver transplantation.
在北美，大面积肝坏死主要归因于病毒感染或接触肝毒素。我们报告了一例不寻常的大面积肝坏死病例，病因是肺小细胞癌的弥漫性肝浸润。这种不寻常的表现包括肿瘤异位产生淀粉酶导致的高淀粉酶血症。在这个肝移植时代，在肝移植前对暴发性或急性肝衰竭进行鉴别诊断时考虑恶性肿瘤很重要。
