Andersson S G, Kurland C G
Dept of Molecular Biology, Uppsala University, Sweden.
Trends Microbiol. 1998 Jul;6(7):263-8. doi: 10.1016/s0966-842x(98)01312-2.
Small, asexual populations are expected to accumulate deleterious substitutions and deletions in an irreversible manner, which in the long-term will lead to mutational meltdown and genome decay. Here, we discuss the influence of such reductive processes on the evolution of genomes that replicate within the domain of a host genome.
小型无性种群预计会以不可逆的方式积累有害的替换和缺失，从长远来看，这将导致突变崩溃和基因组衰退。在此，我们讨论此类还原过程对在宿主基因组范围内复制的基因组进化的影响。
