Kyzer S, Charuzi I
Department of Surgery B, E. Wolfson Medical Center, Holon, Israel.
World J Surg. 1998 Sep;22(9):998-1001. doi: 10.1007/s002689900506.
Obstructive sleep apnea (OSA) syndrome occurs in 4% to 9% of middle-aged men and in 1% to 2% of middle-aged women. The incidence of OSA among morbidly obese patients is 12- to 30-fold higher. The pathophysiology of OSA is complex and incompletely understood. The important clinical symptoms of OSA include snoring, daytime sleepiness, restless sleep, morning fatigue, and headaches. The diagnosis is made by polysomnography. The possible sequelae of OSA are hypertension, left and right ventricular hypertrophy, sudden cardiovascular death, and increased risk for brain infarction. Nasal continuous positive airway pressure (nCPAP) appears to be the recommended treatment for OSA. Morbidly obese patients may also benefit from weight reduction gastric surgery.
阻塞性睡眠呼吸暂停（OSA）综合征在4%至9%的中年男性和1%至2%的中年女性中出现。病态肥胖患者中OSA的发病率要高12至30倍。OSA的病理生理学很复杂，尚未完全了解。OSA的重要临床症状包括打鼾、日间嗜睡、睡眠不安、晨起疲劳和头痛。通过多导睡眠图进行诊断。OSA可能的后遗症是高血压、左右心室肥厚、心源性猝死以及脑梗死风险增加。鼻持续气道正压通气（nCPAP）似乎是OSA的推荐治疗方法。病态肥胖患者也可能从减重胃手术中获益。
