大鼠脑5-羟色胺受体位点激活介导的高血压
Hypertension mediated by the activation of the rat brain 5-hydroxytryptamine receptor sites.
作者信息
Krstić M K, Djurković D
出版信息
Experientia. 1976 Sep 15;32(9):1187-9. doi: 10.1007/BF01927618.
PMID:971759
Abstract
5-Hydroxytryptamine (5-HT) administered intraventricularly (i.vent.) in rats produced hypertension without considerable changes in heart rate. After transsection of the spinal cord or i.vent. administration of methysergide, 5-HT failed to produce the pressor effect. Thus, the hypertension results from the activation of 5-HT receptor sites of the rat brain.
摘要
给大鼠脑室内注射5-羟色胺（5-HT）可导致血压升高，而心率无明显变化。脊髓横断或脑室内注射麦角酰二乙胺后，5-HT未能产生升压效应。因此，高血压是由大鼠脑内5-HT受体位点的激活引起的。
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