Upadhyay R R, Ansarin M, Zarintan M H, Shakui P
Experientia. 1976 Sep 15;32(9):1196-7. doi: 10.1007/BF01927623.
Euphorbia serrata latex has initially ingenol-3-palmitate, which by action of silica gel is converted to ingenol-20-palmitate. The former is responsible for the irritant and cocarcinogenic activity of the latex on mouse ear and on mice back skin.
锯齿大戟乳胶最初含有千金二萜醇-3-棕榈酸酯,在硅胶的作用下,它会转化为千金二萜醇-20-棕榈酸酯。前者是乳胶对小鼠耳朵和小鼠背部皮肤产生刺激和促癌活性的原因。