Gutz H, Leslie J F
Genetics. 1976 Aug;83(4):861-6. doi: 10.1093/genetics/83.4.861.
Gene conversion causes deviations from the 2:2 segregation of allele pairs in meiosis. Thus, gene conversion is a potential cause for changes of allele frequencies in populations. Equations are derived for the effects of conversion in a large random-mating population. The influence of gene conversion on allele frequencies is compared with that of spontaneous mutation and meiotic drive.
基因转换导致减数分裂中等位基因对的2:2分离出现偏差。因此,基因转换是种群中等位基因频率发生变化的一个潜在原因。推导了在一个大型随机交配种群中转换效应的方程。将基因转换对等位基因频率的影响与自发突变和减数分裂驱动的影响进行了比较。