Portolani M, Sabbatini A M, Meacci M, Pietrosemoli P, Cermelli C, Lunghi P, Golinelli F, Stacca R
Centre for Diagnosis of Viral Diseases, University Hospital of Modena, Italy.
J Neurovirol. 1998 Aug;4(4):461-4. doi: 10.3109/13550289809114547.
Herpes simplex virus 1 meningo-encephalitis was ascertained in a 63-year-old immunocompetent man. To determine the duration of the persistence of herpesvirus DNA in the central nervous system, the cerebrospinal fluid was periodically monitored by polymerase chain reaction for 53 days. In addition to HSV-1, Epstein-Barr virus DNA was detected in the cerebrospinal fluid 9 days after disease onset. The possible meaning of the Epstein-Barr virus DNA finding is discussed.
一名63岁免疫功能正常的男性被确诊为单纯疱疹病毒1型脑膜脑炎。为确定疱疹病毒DNA在中枢神经系统中的持续时间，通过聚合酶链反应对脑脊液进行了53天的定期监测。除了HSV-1外，在发病9天后的脑脊液中检测到了爱泼斯坦-巴尔病毒DNA。文中讨论了爱泼斯坦-巴尔病毒DNA检测结果的可能意义。
