Sugarman J, Kaplan L, Cogswell B, Olson J
Duke University Medical Center, Durham, North Carolina, USA.
J Womens Health. 1998 Aug;7(6):747-57. doi: 10.1089/jwh.1998.7.747.
Promising clinical results suggest that umbilical cord blood (UCB) collected after delivery of a child may have many advantages over bone marrow for transplantation. As there are an increasing number of options regarding the collection of UCB, including private and public banking, more pregnant women are likely to be asked to make decisions about UCB collection. We conducted three focus groups with pregnant women to learn about their perspectives on this emerging technology. All the women in these focus groups indicated that they would choose to have UCB collected. Reasons leading to this choice were that the UCB would otherwise be discarded and altruism. Participants indicated that possible reasons to decide not to have UCB collected include concerns about the safety of the mother and neonate, beliefs about the placenta, threats against confidentiality, rejection of UCB, and the influence of fathers. While feeling confident in making an anticipatory decision about UCB collection, women expressed a clear desire to learn much more about the collection, storage (including distinctions between public and private banking), and use of UCB. In addition, they believed that recruitment for UCB collection should occur after sufficient education about UCB and certainly not after delivery and collection. These data will be useful in guiding efforts to help women make decisions about having UCB collected and in developing an appropriate recruitment and informed consent process for donating UCB to a public bank.
有前景的临床结果表明，孩子出生后采集的脐带血（UCB）在移植方面可能比骨髓具有许多优势。随着脐带血采集的选择越来越多，包括私人储存和公共储存，越来越多的孕妇可能会被要求就脐带血采集做出决定。我们与孕妇进行了三个焦点小组讨论，以了解她们对这项新兴技术的看法。这些焦点小组中的所有女性都表示她们会选择采集脐带血。做出这一选择的原因是脐带血否则将被丢弃以及出于利他主义。参与者指出决定不采集脐带血的可能原因包括对母亲和新生儿安全的担忧、对胎盘的看法、对保密性的威胁、对脐带血的排斥以及父亲的影响。虽然对就脐带血采集做出前瞻性决定感到自信，但女性明确表示希望更多地了解脐带血的采集、储存（包括公共储存和私人储存的区别）以及使用情况。此外，她们认为脐带血采集的招募应该在对脐带血进行充分教育之后进行，肯定不能在分娩和采集之后。这些数据将有助于指导相关工作，帮助女性就采集脐带血做出决定，并为向公共库捐赠脐带血制定适当的招募和知情同意程序。
