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[尼日尔尼亚美婴儿非性病性梅毒螺旋体病的血清学研究]

[Serologic studies of non-venereal treponematoses in infants in Niamey, Niger].

作者信息

Julvez J, Michault A, Kerdelhue V

机构信息

Département de Santé Publique, Faculté des Sciences de la Santé, Niamey, Niger.

出版信息

Med Trop (Mars). 1998;58(1):38-40.

PMID:9718553
Abstract

Though no longer reported by health centers, non-venereal treponematoses is still endemic in both arid (Bejel) and Sahelo-soudanian (Pian) areas of Niger. This study describes randomized TPHA testing carried out among children under 5 years of age living in three different sections of Niamey. Clinical examination was not performed before testing. In the overall sample of 183 children, the percent of positive tests was 12.0% with no difference according to place of residence or age. Only 3 of 37 children under the age of 12 months were seropositive Relative levels were too high to be dismissed as serological artifacts. The most likely explanation for the high antitreponemic antibodies is endemic syphilis, or Bejel, which is increasing in this region. Results in children under the age of 12 months suggest that congenital syphilis is uncommon.

摘要

尽管卫生中心不再报告,但非性病性梅毒在尼日尔的干旱地区(比杰尔病)和萨赫勒-苏丹地区(品他病)仍然流行。本研究描述了在尼亚美三个不同区域居住的5岁以下儿童中进行的随机梅毒螺旋体血细胞凝集试验(TPHA)检测。检测前未进行临床检查。在183名儿童的总体样本中,检测阳性率为12.0%,根据居住地点或年龄没有差异。12个月以下的37名儿童中只有3名血清呈阳性,相对水平过高,不能作为血清学假象而不予考虑。抗梅毒螺旋体抗体水平高最可能的解释是地方性梅毒,即比杰尔病,该病在该地区正在增加。12个月以下儿童的检测结果表明先天性梅毒并不常见。

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