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惊恐障碍的药物治疗:给家庭医生的建议指南

Pharmacotherapy of panic disorder: proposed guidelines for the family physician.

作者信息

Roy-Byrne P, Stein M, Bystrisky A, Katon W

机构信息

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, USA.

出版信息

J Am Board Fam Pract. 1998 Jul-Aug;11(4):282-90. doi: 10.3122/jabfm.11.4.282.

Abstract

BACKGROUND

Efforts to improve the recognition and treatment of panic disorder in the primary care setting have not resulted in better outcomes. Studies show that even when physicians recognize panic disorder, they do not treat it adequately. Family physicians need specific diagnostic and treatment guidelines when they encounter a patient who has possible panic disorder.

METHODS

Four psychiatrists with expertise in the pharmacotherapy of panic disorder and experience working in the primary care setting reviewed the available treatment literature and developed a consensus treatment algorithm for panic pharmacotherapy in the primary care setting. These proposed guidelines were reviewed for accuracy by 3 additional psychiatric experts and for their applicability to the primary care setting by 2 leading experts on the treatment of mental disorders in primary care.

RESULTS

Guidelines for medication selection, dosing, titration, side-effect management, and maintenance treatment are proposed. Modifications for patients already on psychotropic medication are provided, and indications for psychiatric consultation are specified.

CONCLUSIONS

Panic disorder is a highly treatable condition, and primary care physicians can deliver effective pharmacotherapy if specific guidelines are carefully followed.

摘要

背景

在初级保健机构中,为提高惊恐障碍的识别和治疗水平所做的努力并未带来更好的治疗效果。研究表明,即使医生识别出惊恐障碍,他们也没有进行充分的治疗。当家庭医生遇到可能患有惊恐障碍的患者时,需要具体的诊断和治疗指南。

方法

四位在惊恐障碍药物治疗方面具有专业知识且有在初级保健机构工作经验的精神科医生回顾了现有的治疗文献,并制定了初级保健机构中惊恐障碍药物治疗的共识治疗算法。另外三位精神科专家对这些拟议的指南进行了准确性审查,两位初级保健机构精神障碍治疗领域的顶尖专家对其在初级保健机构中的适用性进行了审查。

结果

提出了药物选择、剂量、滴定、副作用管理和维持治疗的指南。给出了对已服用精神药物患者的调整建议,并明确了精神科会诊的指征。

结论

惊恐障碍是一种高度可治疗的疾病,如果严格遵循具体指南,初级保健医生可以提供有效的药物治疗。

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