布鲁氏菌属粗糙型菌的内毒素活性
Endotoxic activity of rough organisms of Brucella species.
作者信息
Jones L M, Diaz R, Berman D T
出版信息
Infect Immun. 1976 Jun;13(6):1638-41. doi: 10.1128/iai.13.6.1638-1641.1976.
Abstract
A rough-specific antigen extracted from the rough species Brucella ovis and lipopolysaccharide extracted from smooth Brucella abortus demonstrated equivalent levels of activity in tests for mouse lethality and limulus lysate clotting activity. Acetone-extracted whole cells of B. ovis and of B. canis and of a rough mutant of B; abortus had the same toxicity for mice, but it was not possible to extract endotoxin from B. canis by the methods used.
摘要
从绵羊种布鲁氏菌提取的粗糙特异性抗原以及从流产布鲁氏菌光滑型提取的脂多糖，在小鼠致死性试验和鲎试剂凝血活性试验中表现出同等水平的活性。绵羊种布鲁氏菌、犬种布鲁氏菌以及流产布鲁氏菌粗糙型突变株的丙酮提取全细胞对小鼠具有相同毒性，但采用所用方法无法从犬种布鲁氏菌中提取内毒素。
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本文引用的文献
1
Some structural and biological properties of Brucella endotoxin.布鲁氏菌内毒素的一些结构和生物学特性。
Infect Immun. 1970 Feb;1(2):174-82. doi: 10.1128/iai.1.2.174-182.1970.
2
Biochemical properties of virulent and avirulent strains of brucellae.布鲁氏菌强毒株和无毒株的生化特性
Ann N Y Acad Sci. 1960 Nov 21;88:1155-66. doi: 10.1111/j.1749-6632.1960.tb20106.x.
3
Experimental studies on the significance of endotoxin in the pathogenesis of brucellosis.内毒素在布鲁氏菌病发病机制中的意义的实验研究。
J Clin Invest. 1954 Apr;33(4):540-8. doi: 10.1172/JCI102924.
4
A new method for the extraction of R lipopolysaccharides.一种提取R脂多糖的新方法。
Eur J Biochem. 1969 Jun;9(2):245-9. doi: 10.1111/j.1432-1033.1969.tb00601.x.
5
Characteristics of a newly-recognized species of Brucella responsible for infectious canine abortions.一种新确认的导致犬传染性流产的布鲁氏菌物种的特征。
Cornell Vet. 1968 Oct;48(4):579-92.
6
Taxonomic position in the genus Brucella of the causative agent of canine abortion.犬流产病原体在布鲁氏菌属中的分类地位。
J Bacteriol. 1968 Feb;95(2):625-30. doi: 10.1128/jb.95.2.625-630.1968.
7
Increased host resistance to infection elicited by lipopolysaccharides from Brucella abortus.流产布鲁氏菌脂多糖引发的宿主抗感染能力增强。
Proc Soc Exp Biol Med. 1969 Sep;131(4):1376-81. doi: 10.3181/00379727-131-34111.
8
Chemical composition and biological properties of the endotoxin of Brucella abortus.流产布鲁氏菌内毒素的化学成分与生物学特性
J Bacteriol. 1965 Oct;90(4):895-902. doi: 10.1128/jb.90.4.895-902.1965.
9
Biologically active endotoxins from Salmonella mutants deficient in O- and R-polysaccharides and heptose.来自缺乏O-多糖、R-多糖和庚糖的沙门氏菌突变体的生物活性内毒素。
J Bacteriol. 1967 Nov;94(5):1320-6. doi: 10.1128/jb.94.5.1320-1326.1967.
10
Studies of antigens for complement fixation and gel diffusion tests in the diagnosis of infections caused by Brucella ovis and other Brucella.用于补体结合试验和凝胶扩散试验的抗原在绵羊布鲁氏菌及其他布鲁氏菌所致感染诊断中的研究
Appl Microbiol. 1972 May;23(5):894-902. doi: 10.1128/am.23.5.894-902.1972.
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