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[因主动脉炎导致人工瓣膜脱离病例采用冷冻保存同种异体移植物进行主动脉根部置换术]

[Aortic root replacement by cryopreserved homograft for prosthetic valve detachment case due to aortitis].

作者信息

Yamamoto T, Makuuchi H, Naruse Y, Kobayashi T, Goto M, Nonaka K

机构信息

Department of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.

出版信息

Jpn J Thorac Cardiovasc Surg. 1998 Jun;46(6):565-9. doi: 10.1007/BF03250601.

DOI:10.1007/BF03250601
PMID:9720380
Abstract

We present a surgical case of a 35-year-old man with aortitis. He had been performed the reconstruction of the right common carotid artery with a saphenous vein graft at 23 years old for his ruptured aneurysm by aortitis. The aortic valve replacement and CABG (LITA to LAD, SVG to D1 and SVG to RCA) were performed for aortic regurgitation and aneurysms of coronary arteries two years ago. The diastolic murmur was first heard at 18 months after the operation. The echocardiography on admission showed an abnormal movement of the prosthetic valve with perivalvular leakage. At the second operation, the valve dehiscence was observed. Although the tissues around the dehiscence was friable and edematous, there were no signs of vegetation nor abscess formation. His aortic root was replaced with a cryopreserved aortic allograft conduit. His postoperative course was uneventful and aortography revealed neither aortic regurgitation nor stenosis of the coronary artery or SVGs. We think the softness of the allograft valve ring is favorable in valve detachment cases due to not only infection but also aortitis, to prevent redetachment.

摘要

我们报告一例35岁主动脉炎男性患者的外科手术病例。他在23岁时因主动脉炎导致动脉瘤破裂,接受了右颈总动脉用大隐静脉移植的重建手术。两年前,因主动脉瓣反流和冠状动脉瘤进行了主动脉瓣置换术和冠状动脉旁路移植术(左内乳动脉至左前降支、大隐静脉至第一对角支、大隐静脉至右冠状动脉)。术后18个月首次听到舒张期杂音。入院时超声心动图显示人工瓣膜运动异常伴瓣周漏。在第二次手术中,观察到瓣膜裂开。尽管裂开周围的组织脆弱且水肿,但没有赘生物或脓肿形成的迹象。他的主动脉根部用冷冻保存的主动脉同种异体移植管道进行了置换。他的术后过程平稳,主动脉造影显示既无主动脉瓣反流,冠状动脉或大隐静脉移植血管也无狭窄。我们认为,同种异体移植瓣膜环的柔软性不仅在因感染而且在因主动脉炎导致的瓣膜脱离病例中有利于防止再次脱离。

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引用本文的文献

1
Late aneurysm formation of Valsalva sinus after aortic valve replacement due to Takayasu's arteritis.大动脉炎所致主动脉瓣置换术后瓦氏窦晚期动脉瘤形成
Heart Vessels. 2015 Jul;30(4):558-62. doi: 10.1007/s00380-014-0501-z. Epub 2014 Mar 28.

本文引用的文献

1
Cell viability of aortic allografts after long-term cryopreservation and clinical application to aortic root replacement in a patient with aortitis.长期冷冻保存后主动脉同种异体移植物的细胞活力及其在一名大动脉炎患者主动脉根部置换中的临床应用。
Cardiovasc Surg. 1995 Apr;3(2):231-4. doi: 10.1016/0967-2109(95)90902-h.
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Early and late results of aortic root replacement with antibiotic-sterilized aortic homograft.抗生素消毒主动脉同种异体移植物置换主动脉根部的早期和晚期结果。
J Thorac Cardiovasc Surg. 1988 Apr;95(4):696-704.
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Technical modification of aortic valve replacement in aortitis syndrome--report of a case.
主动脉炎综合征主动脉瓣置换术的技术改良——1例报告
Jpn J Surg. 1989 Mar;19(2):232-6. doi: 10.1007/BF02471592.
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Allograft aortic valve implantation: techniques for all types of aortic valve and root pathology.
Ann Thorac Surg. 1989 Oct;48(4):600-9. doi: 10.1016/s0003-4975(10)66877-4.
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Surgical consideration of aortitis involving the aortic root.累及主动脉根部的主动脉炎的外科治疗考量
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Homograft replacement of aortic valve and ascending aorta in a patient with non-specific giant cell aortitis.非特异性巨细胞性主动脉炎患者主动脉瓣及升主动脉同种异体移植置换术
Br Heart J. 1977 May;39(5):581-5. doi: 10.1136/hrt.39.5.581.
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Takayasu's arteritis. Clinical study of 107 cases.高安动脉炎。107例临床研究。
Am Heart J. 1977 Jan;93(1):94-103. doi: 10.1016/s0002-8703(77)80178-6.