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本文引用的文献

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Site-specific insertion of a SINE-like element, Cp1, into centromeric tandem repeats from Chironomus pallidivittatus.一种类似短分散元件(SINE)的元件Cp1位点特异性插入到苍白摇蚊着丝粒串联重复序列中。
J Mol Biol. 1998 Jul 31;280(5):811-21. doi: 10.1006/jmbi.1998.1896.
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Molecular structure of a functional Drosophila centromere.功能性果蝇着丝粒的分子结构。
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Purification and characterization of a CENP-B homologue protein that binds to the centromeric K-type repeat DNA of Schizosaccharomyces pombe.与粟酒裂殖酵母着丝粒K型重复DNA结合的CENP - B同源蛋白的纯化与鉴定
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Centromeres, CENP-B and Tigger too.着丝粒、着丝粒蛋白B以及转座子Tigger。
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A centromere DNA-binding protein from fission yeast affects chromosome segregation and has homology to human CENP-B.来自裂殖酵母的一种着丝粒DNA结合蛋白影响染色体分离,并且与人类着丝粒蛋白B具有同源性。
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Surprising deficiency of CENP-B binding sites in African green monkey alpha-satellite DNA: implications for CENP-B function at centromeres.非洲绿猴α卫星DNA中着丝粒蛋白B(CENP-B)结合位点的惊人缺乏:对CENP-B在着丝粒功能的影响
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Return of the H-word (heterochromatin).“异染色质”(H字)的回归。
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在苍白摇蚊中具有类似着丝粒蛋白B框基序的散布着丝粒元件。

Interspersed centromeric element with a CENP-B box-like motif in Chironomus pallidivittatus.

作者信息

López C C, Edström J E

机构信息

Department of Genetics, Lund University, Sölvegatan 29, S-22362 Lund, Sweden.

出版信息

Nucleic Acids Res. 1998 Sep 15;26(18):4168-72. doi: 10.1093/nar/26.18.4168.

DOI:10.1093/nar/26.18.4168
PMID:9722636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC147845/
Abstract

Short mobile elements are present in different recombined forms as interspersed GC-rich islands between AT rich centromeric 155 bp tandem repeats in the dipteran Chironomus pallidivittatus . The basic element is 80 bp long, has a pronounced invert repeat structure and contains a 17 bp segment similar to the CENP-B box in mammals. The element inserts into a specific site of the 155 bp repeat in a defined orientation surrounded by 2 bp direct repeats. The total number per genome of the main variant is <20. Elements can be present in all centromeres from C.pallidivittatus and the sibling species Chironomus tentans with pronounced differences in distribution within and between species.

摘要

在双翅目昆虫苍白摇蚊(Chironomus pallidivittatus)富含AT的着丝粒155 bp串联重复序列之间,短移动元件以不同的重组形式存在,呈散布的富含GC的岛状。基本元件长80 bp,具有明显的反向重复结构,并包含一个与哺乳动物CENP - B框相似的17 bp片段。该元件以特定方向插入到155 bp重复序列的特定位点,周围有2 bp的直接重复序列。主要变体的每个基因组总数小于20个。这些元件可存在于苍白摇蚊以及其近缘物种细摇蚊(Chironomus tentans)的所有着丝粒中,在物种内部和物种之间的分布存在明显差异。