在苍白摇蚊中具有类似着丝粒蛋白B框基序的散布着丝粒元件。
Interspersed centromeric element with a CENP-B box-like motif in Chironomus pallidivittatus.
作者信息
López C C, Edström J E
机构信息
Department of Genetics, Lund University, Sölvegatan 29, S-22362 Lund, Sweden.
出版信息
Nucleic Acids Res. 1998 Sep 15;26(18):4168-72. doi: 10.1093/nar/26.18.4168.
Abstract
Short mobile elements are present in different recombined forms as interspersed GC-rich islands between AT rich centromeric 155 bp tandem repeats in the dipteran Chironomus pallidivittatus . The basic element is 80 bp long, has a pronounced invert repeat structure and contains a 17 bp segment similar to the CENP-B box in mammals. The element inserts into a specific site of the 155 bp repeat in a defined orientation surrounded by 2 bp direct repeats. The total number per genome of the main variant is <20. Elements can be present in all centromeres from C.pallidivittatus and the sibling species Chironomus tentans with pronounced differences in distribution within and between species.
摘要
在双翅目昆虫苍白摇蚊（Chironomus pallidivittatus）富含AT的着丝粒155 bp串联重复序列之间，短移动元件以不同的重组形式存在，呈散布的富含GC的岛状。基本元件长80 bp，具有明显的反向重复结构，并包含一个与哺乳动物CENP - B框相似的17 bp片段。该元件以特定方向插入到155 bp重复序列的特定位点，周围有2 bp的直接重复序列。主要变体的每个基因组总数小于20个。这些元件可存在于苍白摇蚊以及其近缘物种细摇蚊（Chironomus tentans）的所有着丝粒中，在物种内部和物种之间的分布存在明显差异。
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