多重耐药鼠伤寒沙门氏菌对新型氟喹诺酮衍生物的体外敏感性
In vitro susceptibility of multiple drug resistant Salmonella typhimurium to newer fluroquinolone derivatives.
作者信息
Shetty M, Shivananda P G
机构信息
Department of Microbiology, Kasturba Medical College, Manipal.
出版信息
Indian J Pathol Microbiol. 1995 Oct;38(4):365-8.
PMID:9726145
Abstract
A total of 105 strains of Salmonella typhimurium resistant to Ampicillin, Co-trimoxazole and Nalidixic acid were included in the present study. Among the new line of Fluroquinolones resistance to Ciprofloxacin (3.8%), Norflox (16.19%) and Ofloxacin (24.76%) was very low as compared to older antibiotics. All the 3 fluoroquinolones had MIC values less than 1 mcg/ml.
摘要
本研究共纳入了105株对氨苄西林、复方新诺明和萘啶酸耐药的鼠伤寒沙门氏菌。在新一代氟喹诺酮类药物中，对环丙沙星（3.8%）、诺氟沙星（16.19%）和氧氟沙星（24.76%）的耐药率与 older antibiotics相比非常低。所有这3种氟喹诺酮类药物的MIC值均小于1微克/毫升。 （原文中“older antibiotics”表述有误，推测可能是“older-line antibiotics”之类的表述，根据上下文，这里应该是指与新一代氟喹诺酮类药物相比，老一代抗生素）
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