Fuller P, Picciotto A, Davies M, McKenzie S A
Queen Elizabeth Hospital for Children, London, UK.
Eur Respir J. 1998 Aug;12(2):426-31. doi: 10.1183/09031936.98.12020426.
This study aimed to determine whether cough at night keeps children awake, to describe the relationship between children's cough and sleep and to report parents' perceptions of their children's cough and sleep. Thirty-nine children with reported persistent cough at night (>3 weeks) were recruited and studied for 6 nights by video-recording. Coughs were counted and sleep state was coded for awake, restless sleep and quiet sleep. The relationships between cough and sleep state between subjects and within subjects were examined by correlation and regression. After night 2 the parents were asked whether their child had coughed or had disturbed sleep and after night 6 they were asked whether there had been any change. There was a weak relationship between log percentage of the night awake and log number of coughs (r=0.13, SE 0.036), and log (percentage of the night awake plus restless sleep) and log number of coughs (r=0.016, SE 0.0071). If the relationship between cough and sleep state is causal, halving the number of coughs will reduce the percentage of the night awake by 9% (95% confidence interval (CI) 4-15%) and percentage awake and restless by 1% (95% CI 0-2%). All but one parent correctly identified coughing and 82% detected change. Most could not comment on their child's sleep. Improvement in cough would result in little reduction in either the percentage of the night awake or awake and restless in the average child in the population studied. Parents could detect whether their children were coughing but not whether their sleep was disturbed.
本研究旨在确定夜间咳嗽是否会使儿童保持清醒,描述儿童咳嗽与睡眠之间的关系,并报告家长对其子女咳嗽和睡眠的看法。招募了39名报告有夜间持续性咳嗽(超过3周)的儿童,并通过视频记录对他们进行了6个晚上的研究。统计咳嗽次数,并将睡眠状态编码为清醒、睡眠不安和安静睡眠。通过相关性和回归分析检查了受试者之间以及受试者内部咳嗽与睡眠状态之间的关系。在第2晚之后,询问家长他们的孩子是否咳嗽或睡眠受到干扰,在第6晚之后,询问他们是否有任何变化。夜间清醒时间的对数百分比与咳嗽次数的对数之间存在微弱关系(r=0.13,标准误0.036),夜间清醒时间的对数百分比与睡眠不安时间的对数之和与咳嗽次数的对数之间存在微弱关系(r=0.016,标准误0.0071)。如果咳嗽与睡眠状态之间的关系是因果关系,咳嗽次数减半将使夜间清醒时间的百分比降低9%(95%置信区间(CI)4-15%),使清醒和睡眠不安时间的百分比降低1%(95%CI 0-2%)。除一名家长外,所有家长都正确识别出了咳嗽,82%的家长察觉到了变化。大多数家长无法对孩子的睡眠情况发表评论。在所研究的总体中,咳嗽症状的改善对平均儿童夜间清醒时间或清醒和睡眠不安时间的百分比几乎没有降低作用。家长能够察觉到孩子是否咳嗽,但无法察觉到孩子的睡眠是否受到干扰。