Hurd R E, Gurr D, Sailasuta N
GE Medical Systems, Fremont, California 94539, USA.
Magn Reson Med. 1998 Sep;40(3):343-7. doi: 10.1002/mrm.1910400302.
A method is introduced for obtaining proton spectra in vivo with all the advantages of a full water signal. The method, based on F1 oversampled J-resolved spectroscopy, makes it possible to separate metabolite signals from unwanted baseline artifacts. The dominant water resonance is used as a 2D reference signal for the phase-sensitive reconstruction of the 2D J-resolved metabolite spectra. The powerful specificity of this method is demonstrated with model compound spectra, phantoms, and in vivo examples.
