Gibellini D, Panaya R, Rumpianesi F
Department of Clinical and Experimental Medicine-Microbiology Section, S. Orsola General Hospital, University of Bologna, Italy.
Zentralbl Bakteriol. 1998 Jul;288(1):35-43. doi: 10.1016/s0934-8840(98)80095-9.
The role of programmed cell death (apoptosis) in LLC-MK2 cells infected with Chlamydia trachomatis LGV2 serotype and Chlamydia psittaci 6BC strain was investigated using flow cytometry and TUNEL procedures. The number of apoptotic cells was significantly higher at 72 and 96 hours post infection in the Chlamydia infected cell cultures in comparison with mock-infected cells. We postulate the apoptotic process to be a mechanism induced by C. trachomatis and C. psittaci infection in LLC-MK2 cells.
利用流式细胞术和TUNEL法研究了细胞程序性死亡（凋亡）在感染沙眼衣原体LGV2血清型和鹦鹉热衣原体6BC菌株的LLC-MK2细胞中的作用。与模拟感染的细胞相比，衣原体感染的细胞培养物在感染后72小时和96小时时，凋亡细胞数量显著更高。我们推测凋亡过程是沙眼衣原体和鹦鹉热衣原体感染LLC-MK2细胞诱导的一种机制。
