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1
Differential susceptibility of chlamydiae to exogenous fibroblast interferon.衣原体对外源成纤维细胞干扰素的敏感性差异
Infect Immun. 1983 Feb;39(2):1004-5. doi: 10.1128/iai.39.2.1004-1005.1983.
2
Division of single host cells after infection with chlamydiae.衣原体感染后单个宿主细胞的分裂
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Attachment defect in mouse fibroblasts (L cells) persistently infected with Chlamydia psittaci.持续感染鹦鹉热衣原体的小鼠成纤维细胞（L细胞）中的黏附缺陷。
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4
Induction of apoptosis by Chlamydia psittaci and Chlamydia trachomatis infection in tissue culture cells.鹦鹉热衣原体和沙眼衣原体感染在组织培养细胞中诱导细胞凋亡
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Persistent infection of mouse fibroblasts (L cells) with Chlamydia psittaci: evidence for a cryptic chlamydial form.鹦鹉热衣原体对小鼠成纤维细胞（L细胞）的持续感染：隐匿性衣原体形态的证据。
Infect Immun. 1980 Dec;30(3):874-83. doi: 10.1128/iai.30.3.874-883.1980.
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Am J Vet Res. 1996 Dec;57(12):1720-5.
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Amino acid requirements of strains of Chlamydia trachomatis and C. psittaci growing in McCoy cells: relationship with clinical syndrome and host origin.沙眼衣原体和鹦鹉热衣原体菌株在 McCoy 细胞中生长时的氨基酸需求：与临床综合征和宿主来源的关系。
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Low-nutrient induction of abnormal chlamydial development: a novel component of chlamydial pathogenesis?低营养诱导衣原体异常发育：衣原体致病机制的一个新组成部分？
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Synthesis of disulfide-bonded outer membrane proteins during the developmental cycle of Chlamydia psittaci and Chlamydia trachomatis.鹦鹉热衣原体和沙眼衣原体发育周期中双硫键结合外膜蛋白的合成
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Characterization of miniature pig kidney cells and their resistance to chlamydial infection.
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引用本文的文献

1
The sst1 resistance locus regulates evasion of type I interferon signaling by Chlamydia pneumoniae as a disease tolerance mechanism.sst1 抗性基因座通过肺炎衣原体作为疾病耐受机制调节 I 型干扰素信号的逃避。
PLoS Pathog. 2013;9(8):e1003569. doi: 10.1371/journal.ppat.1003569. Epub 2013 Aug 29.
2
Chlamydia muridarum infection elicits a beta interferon response in murine oviduct epithelial cells dependent on interferon regulatory factor 3 and TRIF.鼠衣原体感染在依赖于干扰素调节因子3和TRIF的小鼠输卵管上皮细胞中引发β干扰素反应。
Infect Immun. 2007 Mar;75(3):1280-90. doi: 10.1128/IAI.01525-06. Epub 2006 Dec 18.
3
Differential sensitivities of Chlamydia trachomatis strains to inhibitory effects of gamma interferon.沙眼衣原体菌株对γ干扰素抑制作用的差异敏感性
Infect Immun. 2000 Oct;68(10):6038-40. doi: 10.1128/IAI.68.10.6038-6040.2000.
4
Lymphokine-mediated inhibition of Chlamydia replication in mouse fibroblasts is neutralized by anti-gamma interferon immunoglobulin.抗γ干扰素免疫球蛋白可中和淋巴细胞因子介导的对小鼠成纤维细胞中衣原体复制的抑制作用。
Infect Immun. 1983 Dec;42(3):1152-8. doi: 10.1128/iai.42.3.1152-1158.1983.
5
Selective infection of astrocytes by Chlamydia trachomatis in primary mixed neuron-glial cell cultures.沙眼衣原体在原代混合神经元-神经胶质细胞培养物中对星形胶质细胞的选择性感染。
Infect Immun. 1986 Dec;54(3):913-6. doi: 10.1128/iai.54.3.913-916.1986.
6
Interaction of chlamydiae and host cells in vitro.衣原体与宿主细胞在体外的相互作用。
Microbiol Rev. 1991 Mar;55(1):143-90. doi: 10.1128/mr.55.1.143-190.1991.

本文引用的文献

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Effect of Interferon and Interferon Inducers on Infections with a Nonviral Intracellular Microorganism, Chlamydia trachomatis.干扰素和干扰素诱导剂对非病毒细胞内微生物沙眼衣原体感染的影响。
Infect Immun. 1971 Jun;3(6):825-32. doi: 10.1128/iai.3.6.825-832.1971.
2
Chlamydiae.衣原体
Annu Rev Microbiol. 1980;34:285-309. doi: 10.1146/annurev.mi.34.100180.001441.
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Inhibition of TRIC agents by virus-induced interferon.病毒诱导的干扰素对TRIC因子的抑制作用
Proc Soc Exp Biol Med. 1966 Jun;122(2):417-21. doi: 10.3181/00379727-122-31150.
4
Lack of deoxyribonucleic acid homology between species of the genus Chlamydia.衣原体属各物种之间缺乏脱氧核糖核酸同源性。
J Bacteriol. 1968 Oct;96(4):1421-3. doi: 10.1128/jb.96.4.1421-1423.1968.
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Production of high-titered interferon in cultures of human diploid cells.在人二倍体细胞培养物中产生高滴度干扰素。
Antimicrob Agents Chemother. 1972 Dec;2(6):476-84. doi: 10.1128/AAC.2.6.476.
6
Immunochemical studies on chlamydial group antigen (presence of a 2-keto-3-deoxycarbohydrate as immunodominant group).衣原体属群抗原的免疫化学研究（作为免疫显性基团的2-酮-3-脱氧碳水化合物的存在）
J Immunol. 1972 Jul;109(1):116-22.
7
Induction of interferon by the Bour strain of trachoma in HeLa 229 cells.
Am J Ophthalmol. 1967 May;63(5):Suppl:1110-5. doi: 10.1016/0002-9394(67)94091-3.
8
Competition between Chlamydia psittaci and L cells for host isoleucine pools: a limiting factor in chlamydial multiplication.鹦鹉热衣原体与L细胞对宿主异亮氨酸库的竞争：衣原体繁殖的一个限制因素。
Infect Immun. 1975 Jul;12(1):211-20. doi: 10.1128/iai.12.1.211-220.1975.
9
Parasite-specified phagocytosis of Chlamydia psittaci and Chlamydia trachomatis by L and HeLa cells.L细胞和HeLa细胞对鹦鹉热衣原体和沙眼衣原体的寄生虫特异性吞噬作用。
Infect Immun. 1978 Feb;19(2):598-606. doi: 10.1128/iai.19.2.598-606.1978.
10
Antigenic analysis of Chlamydiae by two-dimensional immunoelectrophoresis. II. A trachoma-LGV-specific antigen.用二维免疫电泳法对衣原体进行抗原分析。II. 一种沙眼-淋巴肉芽肿性尿道炎特异性抗原。
J Immunol. 1975 Oct;115(4):969-75.

衣原体对外源成纤维细胞干扰素的敏感性差异

Differential susceptibility of chlamydiae to exogenous fibroblast interferon.

作者信息

Byrne G I, Rothermel C D

出版信息

Infect Immun. 1983 Feb;39(2):1004-5. doi: 10.1128/iai.39.2.1004-1005.1983.

DOI:10.1128/iai.39.2.1004-1005.1983
PMID:6832807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC348050/
Abstract

Mouse fibroblasts (L cells) were incubated for 5 h with 1,000 U of murine fibroblast interferon (MuIFN alpha+ beta) per ml and then were infected with either Chlamydia trachomatis (LGV 440), C. psittaci (6BC), or C. psittaci (Cal 10). Intracellular development of C. trachomatis was reduced 90% in interferon-treated cells 24 h after infection when compared with controls, whereas C. psittaci growth was not affected in interferon-treated cells.

摘要

将小鼠成纤维细胞（L细胞）与每毫升1000单位的鼠成纤维细胞干扰素（MuIFNα + β）一起孵育5小时，然后用沙眼衣原体（LGV 440）、鹦鹉热衣原体（6BC）或鹦鹉热衣原体（Cal 10）进行感染。与对照相比，感染后24小时，干扰素处理的细胞中沙眼衣原体的细胞内发育减少了90%，而干扰素处理的细胞中鹦鹉热衣原体的生长未受影响。