Janssen J C, Larner A J, Morris H, Bronstein A M, Farmer S F
Department of Neurology, St Mary's Hospital, London, UK.
J Neurol Neurosurg Psychiatry. 1998 Sep;65(3):380-1. doi: 10.1136/jnnp.65.3.380.
A patient is reported on with isolated upbeating nystagmus with a linear slow phase in whom a solitary lesion, probably inflammatory, was detected radiologically in the dorsal paramedian caudal medulla, encompassing the most caudal of the perihypoglossal nuclei, the nucleus intercalatus of Staderini. The conjunction of a vestibular pattern of nystagmus with this focal lesion runs contrary to a previous suggestion that the nucleus intercalatus may act as a neural integrator for vertical conjugate eye movements.
报告了一名患有孤立性上跳性眼球震颤且慢相呈线性的患者，其在延髓尾端背侧旁正中区域发现了一个可能为炎性的孤立病变，该病变累及舌下神经周核最尾端的部分，即斯塔德林尼中间核。这种眼球震颤的前庭模式与该局灶性病变同时存在，这与之前关于中间核可能作为垂直共轭眼球运动的神经整合器的观点相悖。
