Lalonde J, Turgay A, Hudson J I
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Can J Psychiatry. 1998 Aug;43(6):623-8. doi: 10.1177/070674379804300612.
To assess demographic characteristics and patterns of comorbid disruptive behavior disorders (oppositional defiant disorder [ODD] or conduct disorder [CD]) in subtypes of attention-deficit hyperactivity disorder (ADHD).
One hundred youths consecutively referred to a community child and adolescent mental health clinic and subsequently diagnosed with ADHD by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria were evaluated. The diagnosis was made by a child psychiatrist and was based on information from physicians, parents, teachers, and diagnostic interviews with the youth and their parents.
The major findings were: 1) ADHD combined (C) type was diagnosed in 78% of the subjects, while 15% had inattentive (1) type and 7% had hyperactive-impulsive (HI) type; and 2) patterns of comorbid disruptive behavioural disorders significantly differed among subtypes. Specifically, subjects with the I type showed lower rates of comorbid ODD than those with the C type (33% and 85%; P < 0.001) and HI type (33% and 100%; P = 0.005); subjects with the HI type displayed a higher prevalence of CD than those with the I type (57% and 0%; P = 0.005) and C type (57% and 8%; P = 0.003). These results should be considered tentative because the reliability of the diagnostic procedures was not formally assessed and the number of subjects in the I and HI groups was small.
ADHD subtypes showed significant differences in the distribution of comorbid disruptive behaviour disorders. These results support the utility of ADHD subtypes but should be replicated with a larger sample of I and HI type subjects using more rigorous diagnostic methods.
评估注意缺陷多动障碍(ADHD)各亚型中并存破坏性行为障碍(对立违抗障碍[ODD]或品行障碍[CD])的人口统计学特征及模式。
对连续转诊至社区儿童及青少年心理健康诊所且随后根据《精神障碍诊断与统计手册》(DSM-IV)标准被诊断为ADHD的100名青少年进行评估。诊断由儿童精神科医生做出,基于医生、家长、教师提供的信息以及对青少年及其家长的诊断访谈。
主要发现为:1)78%的受试者被诊断为ADHD合并型(C型),15%为注意力不集中型(I型),7%为多动冲动型(HI型);2)并存破坏性行为障碍的模式在各亚型间存在显著差异。具体而言,I型受试者并存ODD的比例低于C型(33%和85%;P<0.001)和HI型(33%和100%;P = 0.005);HI型受试者CD的患病率高于I型(57%和0%;P = 0.005)和C型(57%和8%;P = 0.003)。由于未正式评估诊断程序的可靠性且I型和HI型组的受试者数量较少,这些结果应视为初步的。
ADHD各亚型在并存破坏性行为障碍的分布上存在显著差异。这些结果支持ADHD亚型的实用性,但应使用更严格的诊断方法,在更大样本的I型和HI型受试者中进行重复验证。