Martinez-Jarreta B, Budowle B, Abecia E, Bell B, Casalod Y, Castellano M
Department of Legal Medicine, University of Zaragoza, Spain.
J Forensic Sci. 1998 Sep;43(5):1094-6.
LDLR, GYPA, HBGG, D7S8, GC (PM loci) and D1S80 are widely used in forensic casework analyses and population data are required to estimate the frequency of a DNA profile. This paper presents the results of a survey aimed at investigating the allele and genotype frequency distribution of these loci in an important Spanish population (Zaragoza, North Spain). Statistical analysis to determine whether allele frequencies were in Hardy-Weinberg equilibrium was carried out as well as to obtain some parameters of medicolegal interest. There was no evidence of association between the alleles of the loci. The Zaragoza sample does not differ substantially from other Caucasian populations.
低密度脂蛋白受体（LDLR）、血型糖蛋白A（GYPA）、β-球蛋白（HBGG）、D7S8、组特异性成分（GC，表现型位点）和D1S80广泛应用于法医案件分析，需要群体数据来估计DNA图谱的频率。本文展示了一项调查结果，该调查旨在研究这些位点在西班牙一个重要群体（西班牙北部萨拉戈萨）中的等位基因和基因型频率分布。进行了统计分析以确定等位基因频率是否处于哈迪-温伯格平衡，并获取一些法医学相关参数。没有证据表明这些位点的等位基因之间存在关联。萨拉戈萨样本与其他高加索人群体没有实质性差异。
