Teichman J M, Vassar G J, Glickman R D
Department of Ophthalmology, University of Texas Health Science Center, San Antonio 78284-7845, USA.
Urology. 1998 Sep;52(3):392-7. doi: 10.1016/s0090-4295(98)00239-8.
To test the hypothesis that holmium:yttrium-aluminum-garnet (YAG) lithotripsy efficiency varies with stone composition.
Single pulses of holmium:YAG energy were delivered using 272-, 365-, 550-, and 940-microm optical fibers to human calculi composed of calcium oxalate monohydrate (COM), calcium hydrogen phosphate dihydrate (CHPD), cystine, magnesium ammonium phosphate hexohydrate (MAPH), and uric acid. Energy/pulse settings were 0.2, 0.5, 1.0, and 1.5 J. Stone crater width and depth were characterized with reflectance light microscopy.
For similar energies overall MAPH yielded the deepest and widest craters. CHPD, cystine, and uric acid yielded craters of intermediate width and depth. COM yielded the smallest craters. Within any given composition, increased pulse energy yielded craters of increased width and depth.
Holmium:YAG lithotripsy efficiency varies with stone composition. The rank order of crater size appears to correlate with thermal threshold for each composition. Increased holmium:YAG energy produces larger craters for all compositions.
检验钬激光：钇铝石榴石（YAG）碎石效率随结石成分变化的假说。
使用272微米、365微米、550微米和940微米的光纤，将单脉冲钬激光能量作用于由一水草酸钙（COM）、二水磷酸氢钙（CHPD）、胱氨酸、六水磷酸镁铵（MAPH）和尿酸组成的人体结石。每个脉冲的能量设置为0.2、0.5、1.0和1.5焦耳。用反射光显微镜对结石坑的宽度和深度进行表征。
总体而言，对于相似的能量，MAPH产生的坑最深且最宽。CHPD、胱氨酸和尿酸产生的坑宽度和深度中等。COM产生的坑最小。在任何给定成分中，增加脉冲能量会使坑的宽度和深度增加。
钬激光：YAG碎石效率随结石成分变化。坑大小的排序似乎与每种成分的热阈值相关。增加钬激光：YAG能量会使所有成分产生更大的坑。
