[多发性硬化症中的主要组织相容性系统]
[Major histocompatibility system in multiple sclerosis].
作者信息
Oger J, Sabouraud O, Fauchet R, Genetet N, Menault F, Genetet B
出版信息
Rev Neurol (Paris). 1976 Feb;132(2):89-97.
PMID:973072
Abstract
The comparison of Histocompatibility Testing in 82 MS Patients and 368 controls is presented. The increase in HL-A7 and decrease in HL-A12 are confirmed. A significant increase in HL-A8 is reported. Mixed Lymphocyte Reaction confirms the LD7a increase (19 out of 24 Multiple Sclerosis patients tested); 100% of the patients bearing the HL-A7 determinant are found to be LD7a. The presence of specific Immune Response genes in Multiple Sclerosis is discussed.
摘要
本文展示了82例多发性硬化症患者与368例对照者的组织相容性检测结果比较。HL - A7增加和HL - A12减少得到了证实。报告显示HL - A8有显著增加。混合淋巴细胞反应证实了LD7a增加（在检测的24例多发性硬化症患者中有19例）；发现携带HL - A7决定簇的患者100%为LD7a。文中还讨论了多发性硬化症中特异性免疫反应基因的存在情况。
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