Hammadeh M Y, Madaan S, Singh M, Philp T
Department of Urology, Whipps Cross Hospital, London, UK.
Eur Urol. 1998 Sep;34(3):188-92. doi: 10.1159/000019710.
Transurethral electrovaporization of the prostate (TUVP) has become a popular, minimally invasive procedure to treat BPH with promising initial results. This study was conducted to compare the efficacy, safety and durability of TUVP with standard TURP. We report the 2-year follow-up.
104 consecutive men with BPH admitted for surgery were randomised to TUVP (52 patients, mean age: 67.5 years) or TURP (52 patients, mean age: 70.2 years). 47 patients in each arm completed 2-year follow-up.
Follow-up data at 2 years show a comparable, significant and maintained improvement in mean IPSS (TUVP: 4.3 vs. TURP: 6.3), quality of life score (TUVP: 1. 1 vs. TURP: 1.7), and maximum flow rate (TUVP: 22.4 vs. TURP: 21.2 ml/s) with fall in mean post-void residual volume (TUVP: 18.8 vs. TURP: 22.8 ml). Postoperative impotence reported in TUVP: 17% vs. TURP: 11% (p = 0.49) and retrograde ejaculation TUVP: 72% vs. TURP: 89% (p = 0.47). Two patients in each arm (4%) had urethral stricture and 2 patients (4%) in the resected group had bladder neck stricture. Four patients in each group required re-operation for residual adenoma during the 2 years (4% in each arm each year).
Our 2 years' follow-up results suggest that TUVP is as effective as standard TURP in the treatment of moderate-sized BPH with comparable durability.
经尿道前列腺电汽化术（TUVP）已成为一种治疗良性前列腺增生（BPH）的常用微创手术，初步结果令人满意。本研究旨在比较TUVP与标准经尿道前列腺切除术（TURP）的疗效、安全性及持久性。我们报告了2年的随访结果。
104例因BPH需手术治疗的男性患者被随机分为TUVP组（52例，平均年龄67.5岁）和TURP组（52例，平均年龄70.2岁）。每组47例患者完成了2年随访。
2年随访数据显示，两组患者的平均国际前列腺症状评分（IPSS）（TUVP组：4.3 vs. TURP组：6.3）、生活质量评分（TUVP组：1.1 vs. TURP组：1.7）及最大尿流率（TUVP组：22.4 vs. TURP组：21.2 ml/s）均有相似、显著且持续的改善，平均残余尿量减少（TUVP组：18.8 vs. TURP组：22.8 ml）。TUVP组术后勃起功能障碍发生率为17%，TURP组为11%（p = 0.49）；TUVP组逆行射精发生率为72%，TURP组为89%（p = 0.47）。每组各有2例患者（4%）发生尿道狭窄，切除组有2例患者（4%）发生膀胱颈狭窄。两组各有4例患者在2年内因残留腺瘤需再次手术（每组每年4%）。
我们的2年随访结果表明，在治疗中度BPH方面，TUVP与标准TURP疗效相当，持久性相似。
