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从高危患者下消化道分离出的念珠菌属对新型半合成棘白菌素LY303366及其他抗真菌药物的敏感性。

Susceptibilities of Candida species isolated from the lower gastrointestinal tracts of high-risk patients to the new semisynthetic echinocandin LY303366 and other antifungal agents.

作者信息

Zhanel G G, Karlowsky J A, Zelenitsky S A, Turik M A, Hoban D J

机构信息

Department of Medical Microbiology, University of Manitoba, Canada

出版信息

Antimicrob Agents Chemother. 1998 Sep;42(9):2446-8. doi: 10.1128/AAC.42.9.2446.

DOI:10.1128/AAC.42.9.2446
PMID:9736582
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC105852/
Abstract

Fifty-two percent of stool specimens collected from 1,200 high-risk patients were colonized with yeasts, primarily Candida albicans (53. 6%) and Candida glabrata (35.7%). Susceptibilities to all antifungal agents tested, including LY303366, were similar to those reported previously for Candida species isolated from blood.

摘要

从1200名高危患者采集的粪便样本中，52%被酵母菌定植，主要是白色念珠菌（53.6%）和光滑念珠菌（35.7%）。对包括LY303366在内的所有测试抗真菌药物的敏感性，与先前报道的从血液中分离出的念珠菌属的敏感性相似。

相似文献

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Susceptibilities of Candida species isolated from the lower gastrointestinal tracts of high-risk patients to the new semisynthetic echinocandin LY303366 and other antifungal agents.从高危患者下消化道分离出的念珠菌属对新型半合成棘白菌素LY303366及其他抗真菌药物的敏感性。
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Antimicrob Agents Chemother. 2000 Feb;44(2):378-81. doi: 10.1128/AAC.44.2.378-381.2000.

本文引用的文献

1
Candidemia in a Canadian tertiary care hospital from 1976 to 1996.1976年至1996年加拿大一家三级护理医院的念珠菌血症。
Diagn Microbiol Infect Dis. 1997 Sep;29(1):5-9. doi: 10.1016/s0732-8893(97)00068-0.
2
In vitro activity of a new semisynthetic echinocandin, LY-303366, against systemic isolates of Candida species, Cryptococcus neoformans, Blastomyces dermatitidis, and Aspergillus species.新型半合成棘白菌素LY-303366对念珠菌属、新生隐球菌、皮炎芽生菌及曲霉属的全身感染分离株的体外活性
Antimicrob Agents Chemother. 1997 Apr;41(4):863-5. doi: 10.1128/AAC.41.4.863.
3
In vitro susceptibilities of clinical yeast isolates to a new echinocandin derivative, LY303366, and other antifungal agents.临床酵母分离株对新型棘白菌素衍生物LY303366及其他抗真菌药物的体外敏感性
Antimicrob Agents Chemother. 1997 Apr;41(4):763-6. doi: 10.1128/AAC.41.4.763.
4
Antifungal dynamics of LY 303366, an investigational echinocandin B analog, against Candida ssp.LY 303366（一种研究中的棘白菌素B类似物）对念珠菌属的抗真菌动力学
Diagn Microbiol Infect Dis. 1996 Nov-Dec;26(3-4):125-31. doi: 10.1016/s0732-8893(96)00202-7.
5
Mechanisms of association of Candida albicans with intestinal mucosa.白色念珠菌与肠黏膜的关联机制。
J Med Microbiol. 1987 Dec;24(4):333-41. doi: 10.1099/00222615-24-4-333.