Davis W L, Goodman D B, Rasmussen H
J Membr Biol. 1978 Jul 5;41(3):225-34. doi: 10.1007/BF01870430.
A study has been conducted to determine the ionic and metabolic requirements for full expression of the hydroosmotic response to antidiuretic hormone in the toad urinary bladder. By appropriate manipulation of incubation conditions it can be shown that there is a pool of serosal sodium necessary for a full hormone response. This serosal sodium pool is not related to the transepithelial sodium transport pool A full hydroosmotic response also requires serosal potassium; however, no specific anion requirement was demonstrated. Additionally, anaerobic or aerobic metabolism support a full hydroosmotic response equally well.
为确定蟾蜍膀胱对抗利尿激素的水渗透反应完全表达所需的离子和代谢条件，进行了一项研究。通过对孵育条件的适当控制，可以表明，完全的激素反应需要浆膜钠池。这个浆膜钠池与跨上皮钠转运池无关。完全的水渗透反应也需要浆膜钾；然而，未证明有特定的阴离子需求。此外，无氧或有氧代谢对完全的水渗透反应的支持程度相同。
