心率增加对正常个体未校正的射血前期/左心室射血时间（PEP/LVET）比值的影响。
Influence of heart rate increase on uncorrected pre-ejection period/left ventricular ejection time (PEP/LVET) ratio in normal individuals.
作者信息
Cokkinos D V, Heimonas E T, Demopoulos J N, Harralambakis A, Tsartsalis G, Gardikas C D
出版信息
Br Heart J. 1976 Jul;38(7):683-8. doi: 10.1136/hrt.38.7.683.
In 26 normal volunteers, increase in heart rate from mean 73-94 +/- 1-97 to 103-61 +/- 2-72/min, by either intravenous atropine administration or rapid right atrial pacing, produced definite changes in the uncorrected systolic time intervals. As expected, total electromechanical systole (QS2) and left ventricular ejection time (LVET) were shortened, while the pre-ejection period (PEP) was unaffected. There was a consistent and significant increase of the PEP/LVET ratio (P less than 0-001). It is postulated that when this ratio is taken to express left ventricular contractility, it should probably be corrected for heart rate. Appropriate regression equations for such a correction were calculated (PEP/LVET=0-249 + 0-0168 HR).
在26名正常志愿者中，通过静脉注射阿托品或快速右心房起搏，心率从平均73 - 94±1 - 97次/分钟增加到103 - 61±2 - 72次/分钟，这使得未校正的收缩期时间间期产生了明确变化。正如预期的那样，总电机械收缩期（QS2）和左心室射血时间（LVET）缩短，而射血前期（PEP）未受影响。PEP/LVET比值持续且显著增加（P＜0.001）。据推测，当用该比值表示左心室收缩力时，可能应该对心率进行校正。计算了用于这种校正的适当回归方程（PEP/LVET = 0.249 + 0.0168 HR）。
Zotero 插件