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孕期血浆催乳素水平。

Plasma prolactin levels during pregnancy.

作者信息

Biswas S, Rodeck C H

出版信息

Br J Obstet Gynaecol. 1976 Sep;83(9):683-7. doi: 10.1111/j.1471-0528.1976.tb00913.x.

DOI:10.1111/j.1471-0528.1976.tb00913.x
PMID:974045
Abstract

Plasma prolactin levels in women who were between 8 and 40 weeks pregnant were determined by a homologous double antibody radioimmunoassay method. There were 980 samples from 839 uncomplicated and 213 samples from 116 complicated pregnancies. Prolactin levels in normal pregnancies varied from 6 ng/ml during early pregnancy to 210 ng/ml near term. A few values beyond the normal range were found in various groups of complicated pregnancies. About 14 per cent of samples from patients with threatened abortion and 7 per cent from patients with hypertension were above the upper normal range. The proportion of values below the 10th centile in patients with a low urinary oestrogen excretion was significantly higher than that in the normal population. Plasma prolactin levels did not seem to be a valuable guide to maternal or fetal well-being.

摘要

采用同源双抗体放射免疫分析法测定了8至40周妊娠女性的血浆催乳素水平。其中,839例无并发症妊娠的样本有980份,116例并发症妊娠的样本有213份。正常妊娠时催乳素水平从妊娠早期的6 ng/ml到接近足月时的210 ng/ml不等。在不同组的并发症妊娠中发现了一些超出正常范围的值。先兆流产患者约14%的样本以及高血压患者7%的样本高于正常范围上限。尿雌激素排泄量低的患者中,低于第10百分位数的值的比例显著高于正常人群。血浆催乳素水平似乎不是评估母体或胎儿健康状况的有价值指标。

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