Kshirsagar M J, Langade D, Patil S, Patki P S
Department of Pharmacology, B.J. Medical College, Pune, India.
Bull World Health Organ. 1998;76(3):271-5.
In 1975 the World Health Assembly requested the Director-General to advise Member States on the selection and procurement of essential drugs corresponding to their national health needs. We report here the results of a study of the prescribing patterns and rational drug utilization of medical practitioners of Pune, an industrial city in the west of India, which was undertaken by analysing their prescriptions. The results indicated a lack of rational prescribing practices by a significant number of practitioners. Fixed-dose formulations dominated the prescribing pattern and generic prescriptions were negligible, with prescriptions for essential drugs accounting for less than 60% of the total number of drugs prescribed. More than 30% of prescriptions were irrational, with the probability of such prescriptions increasing significantly with the number of drugs per prescription. A study of sources of drug formulations available for prescription revealed significantly more fixed-dose combinations, many of which were irrational. These results call for intervention strategies to promote rational drug therapy in India.
1975年,世界卫生大会要求总干事就根据会员国的国家卫生需求选择和采购基本药物向其提供建议。我们在此报告一项对印度西部工业城市浦那的医生处方模式和合理用药情况的研究结果,该研究通过分析他们的处方展开。结果表明,相当数量的医生存在不合理的处方行为。固定剂量制剂在处方模式中占主导地位,通用名处方极少,基本药物的处方占所开药物总数的比例不到60%。超过30%的处方不合理,此类处方的可能性随着每张处方的药物数量显著增加。一项关于可供处方的药物制剂来源的研究显示,固定剂量组合明显更多,其中许多是不合理的。这些结果呼吁采取干预策略以促进印度的合理药物治疗。