• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Direct visualisation of individual gene organisation in Trypanosoma brucei by high-resolution in situ hybridisation.

作者信息

Ersfeld K, Asbeck K, Gull K

机构信息

School of Biological Sciences, 2.205 Stopford Building, University of Manchester, Manchester M13 9PT, UK.

出版信息

Chromosoma. 1998 Sep;107(4):237-40. doi: 10.1007/s004120050302.

DOI:10.1007/s004120050302
PMID:9745048
Abstract

We achieved the direct visualisation of gene organisation in Trypanosoma brucei using fluorescent in situ hybridisation on extended nuclear DNA fibres. We demonstrated the repetitive nature of the tubulin gene cluster, which consists of up to 19 alpha- and beta-tubulin genes arranged in tandem repeats.

摘要

相似文献

1
Direct visualisation of individual gene organisation in Trypanosoma brucei by high-resolution in situ hybridisation.
Chromosoma. 1998 Sep;107(4):237-40. doi: 10.1007/s004120050302.
2
A repetitive protein from Trypanosoma brucei which caps the microtubules at the posterior end of the cytoskeleton.一种来自布氏锥虫的重复性蛋白质,它在细胞骨架的后端封闭微管。
Mol Biochem Parasitol. 1993 Mar;58(1):83-96. doi: 10.1016/0166-6851(93)90093-d.
3
Double-stranded RNA interference in Trypanosoma brucei using head-to-head promoters.使用头对头启动子在布氏锥虫中进行双链RNA干扰。
Mol Biochem Parasitol. 2000 Nov;111(1):67-76. doi: 10.1016/s0166-6851(00)00300-5.
4
Partitioning of large and minichromosomes in Trypanosoma brucei.布氏锥虫中大染色体和微型染色体的分配
Science. 1997 Apr 25;276(5312):611-4. doi: 10.1126/science.276.5312.611.
5
A ribosomal S12-like gene of Trypanosoma brucei.布氏锥虫的一个核糖体S12样基因。
Mol Biochem Parasitol. 1993 Feb;57(2):331-4. doi: 10.1016/0166-6851(93)90208-f.
6
Homologous recombination and stable transfection in the parasitic protozoan Trypanosoma brucei.寄生原生动物布氏锥虫中的同源重组与稳定转染
Science. 1990 Dec 14;250(4987):1583-7. doi: 10.1126/science.2177225.
7
Molecular characterization of the mitochondrial heat shock protein 60 gene from Trypanosoma brucei.布氏锥虫线粒体热休克蛋白60基因的分子特征
Mol Biochem Parasitol. 1995 Oct;74(1):119-23. doi: 10.1016/0166-6851(95)02486-7.
8
Tubulin mRNAs of Trypanosoma brucei.布氏锥虫的微管蛋白信使核糖核酸
J Mol Biol. 1986 Apr 5;188(3):393-402. doi: 10.1016/0022-2836(86)90163-4.
9
Stable transformation of Trypanosoma brucei.布氏锥虫的稳定转化
Mol Biochem Parasitol. 1993 May;59(1):133-42. doi: 10.1016/0166-6851(93)90014-o.
10
Architecture of the Trypanosoma brucei nucleus during interphase and mitosis.布氏锥虫细胞核在间期和有丝分裂期间的结构。
Chromosoma. 2000 Mar;108(8):501-13. doi: 10.1007/s004120050402.

引用本文的文献

1
Development of a TaqMan qPCR assay for trypanosomatid multi-species detection and quantification in insects.开发 TaqMan qPCR assay 用于检测和定量昆虫中的锥虫多物种。
Parasit Vectors. 2023 Feb 14;16(1):69. doi: 10.1186/s13071-023-05687-3.
2
A longitudinal two-year survey of the prevalence of trypanosomes in domestic cattle in Ghana by massively parallel sequencing of barcoded amplicons.通过大规模平行测序加条码扩增子对加纳国内牛种锥虫流行情况进行的为期两年的纵向调查。
PLoS Negl Trop Dis. 2022 Apr 20;16(4):e0010300. doi: 10.1371/journal.pntd.0010300. eCollection 2022 Apr.
3
Functional insights from a surface antigen mRNA-bound proteome.
基于表面抗原 mRNA 结合蛋白组的功能研究
Elife. 2021 Mar 30;10:e68136. doi: 10.7554/eLife.68136.
4
Codon choice directs constitutive mRNA levels in trypanosomes.密码子选择指导锥虫中组成型 mRNA 水平。
Elife. 2018 Mar 15;7:e32467. doi: 10.7554/eLife.32467.
5
An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri.通过对普遍存在于牛科动物中的寄生虫——无巴特氏锥虫(Trypanosoma (Megatrypanum) theileri)的基因组和转录组分析,揭示了锥虫在哺乳动物血液中生存的另一种策略。
Genome Biol Evol. 2017 Aug 1;9(8):2093-2109. doi: 10.1093/gbe/evx152.
6
Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome.非洲锥虫中HAT3对DNA切除的基因座特异性控制及亚端粒VSG重组的抑制
Nucleic Acids Res. 2014 Nov 10;42(20):12600-13. doi: 10.1093/nar/gku900. Epub 2014 Oct 9.
7
Inhibition of mRNA maturation in trypanosomes causes the formation of novel foci at the nuclear periphery containing cytoplasmic regulators of mRNA fate.在原生动物中抑制 mRNA 成熟会导致在核周形成新的焦点,其中包含细胞质中 mRNA 命运的调节因子。
J Cell Sci. 2012 Jun 15;125(Pt 12):2896-909. doi: 10.1242/jcs.099275. Epub 2012 Feb 24.
8
How do trypanosomes change gene expression in response to the environment?锥虫如何响应环境改变基因表达?
Protoplasma. 2012 Apr;249(2):223-38. doi: 10.1007/s00709-011-0282-5. Epub 2011 May 20.
9
Evolution of tubulin gene arrays in Trypanosomatid parasites: genomic restructuring in Leishmania.锥虫寄生虫微管蛋白基因阵列的进化:利什曼原虫中的基因组重组
BMC Genomics. 2006 Oct 18;7:261. doi: 10.1186/1471-2164-7-261.
10
A novel strategy to identify the location of necessary and sufficient cis-acting regulatory mRNA elements in trypanosomes.一种鉴定锥虫中必需且充分的顺式作用调控mRNA元件位置的新策略。
RNA. 2005 Jul;11(7):1108-16. doi: 10.1261/rna.2510505. Epub 2005 May 31.