Federico F, Simone I L, Lucivero V, Defazio G, De Salvia R, Mezzapesa D M, Petruzzellis M, Tortorella C, Livrea P
Department of Neurology and Psychiatry, University of Bari, Italy.
Neurology. 1998 Sep;51(3):892-5. doi: 10.1212/wnl.51.3.892.
Single-volume proton magnetic resonance spectroscopy, localized to basal ganglia, was carried out in 10 patients with primary blepharospasm (PB) to assess the levels of N-acetyl aspartate (NAA), creatine-phosphocreatine, and choline-containing compounds. NAA was reduced significantly in patients compared with control subjects. This result suggests a striatal neuronal loss in PB.