Reichel W
Department of Medicine, Albert Einstein College of Medicine, New York, N.Y., USA.
J Am Geriatr Soc. 1966 May;14(5):431-46. doi: 10.1111/j.1532-5415.1966.tb03069.x.
Various biological aspects of the aging process are reviewed. Aging has multiple causes. First, there is the initial genetic variability in the organism. Second, there is the destructive effect of the environment. Third, there is an accumulation in the somatic cells of changes, mutations or local chemical damage. These changes incapacitate or kill individual cells, and eventually cause a decline in physiological capacity.
本文综述了衰老过程的各种生物学方面。衰老有多种原因。首先,生物体存在初始遗传变异性。其次,环境具有破坏作用。第三,体细胞中存在变化、突变或局部化学损伤的积累。这些变化使单个细胞丧失功能或死亡,最终导致生理能力下降。