Bessell J R, Finch R, Gotley D C, Smithers B M, Nathanson L, Menzies B
Department of Surgery, Mater Private Hospital, Royal Brisbane Hospital and Princess Alexandra Hospital, Brisbane, Australia.
Br J Surg. 2000 Oct;87(10):1341-5. doi: 10.1046/j.1365-2168.2000.01634.x.
Many surgeons practise tailored laparoscopic antireflux surgery in an attempt to prevent postoperative dysphagia. The aim of this study was to determine the effect of 360 degrees fundoplication (Nissen) or 270 degrees fundoplication (Toupet), and the influence of abnormal oesophageal peristalsis, upon postoperative dysphagia.
This was a cohort study from three tertiary referral centres, using dysphagia before laparoscopic fundoplication and 1 year after operation as the main outcome variable. Preoperative oesophageal manometry was performed on all patients.
Some 761 patients underwent Nissen and 85 underwent Toupet fundoplication. Only 2 per cent reported severe postoperative dysphagia. There was a significant selection bias towards the Toupet operation for patients with abnormal oesophageal motility (P < 0.001). For patients whose oesophageal manometric findings were normal there was a significant improvement in dysphagia after Nissen fundoplication (P = 0.02), and no significant change following Toupet fundoplication. There was no significant change in the rate of dysphagia following either method of fundoplication amongst other subgroups in which oesophageal manometry was stratified as non-specific motor disorder, low-amplitude peristalsis, or aperistalsis.
A tailored approach to the degree of fundoplication is unnecessary as patients with dysmotility suffer no more dysphagia after full laparoscopic Nissen fundoplication than those who have a partial Toupet wrap.
许多外科医生实施量身定制的腹腔镜抗反流手术,试图预防术后吞咽困难。本研究的目的是确定360度胃底折叠术(nissen术)或270度胃底折叠术(Toupet术)的效果,以及异常食管蠕动对术后吞咽困难的影响。
这是一项来自三个三级转诊中心的队列研究,以腹腔镜胃底折叠术前和术后1年的吞咽困难作为主要结局变量。对所有患者进行术前食管测压。
约761例患者接受了nissen术,85例接受了Toupet胃底折叠术。只有2%的患者报告有严重的术后吞咽困难。食管动力异常的患者在Toupet手术中存在显著的选择偏倚(P<0.001)。对于食管测压结果正常的患者,nissen胃底折叠术后吞咽困难有显著改善(P=0.02),而Toupet胃底折叠术后无显著变化。在食管测压分层为非特异性运动障碍、低振幅蠕动或无蠕动的其他亚组中,两种胃底折叠术的吞咽困难发生率均无显著变化。
对于动力障碍患者,全腹腔镜nissen胃底折叠术后吞咽困难并不比部分Toupet包裹术患者更严重,因此无需对胃底折叠程度采取量身定制的方法。