Haygood L J, Bennett J D, Brodell R T
Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44483, USA.
Dermatol Surg. 1998 Sep;24(9):1027-31. doi: 10.1111/j.1524-4725.1998.tb04297.x.
Although many treatment modalities have been described for xanthelasma palpebrarum, no single technique has emerged as dominant.
Our purpose was to review the various therapeutic modalities for xanthelasma and to assess the efficacy of topical bichloracetic acid.
Thirteen patients with 25 xanthelasma were treated with topical 100% bichloracetic acid. Efficacy was assessed over a follow-up period of 7 months to 10.5 years (average, 64 months).
Eighty-five percent of patients experienced initial complete clearing, and 72% of their lesions have not required retreatment over an average period of 68 months. Recurrences responded well to repeat treatment. Eighty-three percent of recurrent or poorly responsive lesions were associated with high cholesterol. The most resistant patient had four-lid involvement. Excellent cosmetic results and high patient satisfaction were seen.
Topical bichloracetic acid is a viable alternative to other modalities in the management of xanthelasma. Advantages include simplicity, cost-effectiveness, speed, safety, and efficacy.
尽管已描述了多种睑黄瘤的治疗方式，但尚无单一技术成为主导。
我们的目的是回顾睑黄瘤的各种治疗方式，并评估外用二氯乙酸的疗效。
13例患有25处睑黄瘤的患者接受了外用100%二氯乙酸治疗。在7个月至10.5年（平均64个月）的随访期内评估疗效。
85%的患者最初完全清除，平均68个月期间，72%的病变无需再次治疗。复发病变对重复治疗反应良好。83%的复发性或反应不佳的病变与高胆固醇有关。最具抗性的患者累及四个眼睑。获得了极佳的美容效果和患者高度满意度。
外用二氯乙酸是睑黄瘤治疗中其他方式的可行替代方案。优点包括操作简单、成本效益高、速度快、安全且有效。
