Rothwell M, Anstice H M, Pearson G J
Biomaterials Department, Eastman Dental Institute, London, UK.
J Dent. 1998 Sep;26(7):591-7. doi: 10.1016/s0300-5712(97)00035-3.
The cariostatic action associated with the glass-ionomer cement (GIC) is usually attributed to its sustained release of fluoride. However the ability of the GIC to act as a fluoride reservoir, taking it up from an external source (e.g. toothpaste, mouthwash) and subsequently releasing it over time, may also be a contributory factor. This study investigated the reservoir effect of various recently introduced ion-releasing cements: two resin-modified glass-ionomer cements (Fuji II LC, Vitremer), a compomer (acid-modified composite resin) (Dyract), and a recently introduced conventional glass-ionomer (Fuji IX).
Specimens were exposed to a fluoridated toothpaste after 28 and/or 58 days. The release of fluoride into the storage water, both before and after exposure, was monitored using a differential electrode cell.
There was no significant difference in the fluoride releases from Vitremer and Fuji II LC. These materials released significantly more fluoride than Fuji IX and Dyract. All the materials released more fluoride on the day after exposure to an external fluoride source compared with the day before exposure. Release rates returned to baseline within 3 days. Within the time periods of the study, only the uptake/re-release of Fuji IX was adversely affected by late exposure. All the materials showed an enhanced uptake and release on repeated exposure to the external fluoride source.
All the materials under test (Dyract, Fuji II LC, Vitremer and Fuji IX) released significant amounts of fluoride and reacted positively to exposure to an external fluoride source.
玻璃离子水门汀(GIC)的防龋作用通常归因于其持续释放氟化物。然而,GIC作为氟化物储存库的能力,即从外部来源(如牙膏、漱口水)吸收氟化物并随后随时间释放,也可能是一个促成因素。本研究调查了各种最近推出的释离子水门汀的储存库效应:两种树脂改性玻璃离子水门汀(富士II LC、Vitremer)、一种复合体(酸改性复合树脂)(Dyract)和一种最近推出的传统玻璃离子水门汀(富士IX)。
在28天和/或58天后将样本暴露于含氟牙膏。使用差分电极池监测暴露前后氟化物向储存水中的释放。
Vitremer和富士II LC的氟化物释放量无显著差异。这些材料释放的氟化物明显多于富士IX和Dyract。与暴露前一天相比,所有材料在暴露于外部氟源后的第二天释放出更多的氟化物。释放速率在3天内恢复到基线。在研究时间段内,只有富士IX的吸收/再释放受到后期暴露的不利影响。所有材料在反复暴露于外部氟源时均表现出增强的吸收和释放。
所有受试材料(Dyract、富士II LC、Vitremer和富士IX)均释放大量氟化物,并对暴露于外部氟源产生积极反应。