Coufal F, Linarelli L, James H E, Krous H
Division of Neurosurgery, School of Medicine of the University of California, San Diego, and Children's Hospital of San Diego, Calif., USA.
Pediatr Neurosurg. 1998 Jul;29(1):19-22. doi: 10.1159/000028679.
Cushing's disease is described in a child with a suprasellar germinoma. The patient presented with all of the classic stigmata of Cushing's disease as well as diabetes insipidus, but after surgical resection of the lesion was found to have pathology incompatible with an ACTH-secreting tumor. We believe that this is the first reported incidence of Cushing's disease associated with a suprasellar germinoma. The implications of this unusual association are discussed.
一名患有鞍上生殖细胞瘤的儿童被诊断为库欣病。该患者表现出库欣病的所有典型体征以及尿崩症,但在手术切除病变后发现病理结果与促肾上腺皮质激素分泌肿瘤不符。我们认为这是首次报道的与鞍上生殖细胞瘤相关的库欣病病例。本文讨论了这种不寻常关联的意义。