Suppr超能文献

III期股骨头坏死患者行髓芯减压术预后的影像学预测因素

Radiographic predictors of outcome of core decompression for hips with osteonecrosis stage III.

作者信息

Mont M A, Jones L C, Pacheco I, Hungerford D S

机构信息

Department of Orthopaedic Surgery, Good Samaritan Hospital, Baltimore, MD 21239, USA.

出版信息

Clin Orthop Relat Res. 1998 Sep(354):159-68. doi: 10.1097/00003086-199809000-00019.

Abstract

Various investigators have studied the prognostic influence of various demographic, laboratory, and radiographic parameters on outcome for different treatment methods for osteonecrosis of the femoral head. A cross sectional study was done of 52 patients (68 hips) who had a core decompression for Ficat and Arlet Stage III osteonecrosis of the femoral head. The purpose of this study was to evaluate the prognostic significance of various radiographic factors for risk of disease progression after treatment with core decompression. Radiographic parameters included Steinberg stages (III or IV), Ohzono stage (central or lateral location), amount of head depression, extent of crescent sign arc, and extent of lesion by Kerboul combined necrotic angle measurements. Patient outcome assessment was at a followup mean of 12 years (range, 4-18 years) after core decompression. Overall, 20 of the 68 hips (29%) had satisfactory outcomes. Of the 44 hips with Steinberg Stage III disease, 18 (41%) underwent total hip arthroplasty. In comparison, in the Steinberg Stage IV hips, 22 of 24 hips (92%) underwent arthroplasty. Ohzono Stage B lesions had 50% survival (eight of 16 hips) compared with 23% survival (12 of 52 hips) for Ohzono Stage C. Hips with combined necrotic angles greater than 250 degrees had 16% survival (seven of 45) which can be compared with 57% survival (13 of 23) for hips with angles less than 250 degrees. The best multiple regression model for a satisfactory outcome was a Steinberg Stage III hip (no head depression), a central lesion (Ohzono Stage B), and a small lesion (< 250 degrees combined necrotic angle). With this combination, there were 89% satisfactory outcomes (8 of 9 hips). Conversely, the best generalized linear model for unsatisfactory outcomes (0 hips surviving of 14) was Steinberg Stage IV disease (head depression), lateral location (Ohzono Stage C lesion), and a large extent of the lesion (> 250 degrees combined necrotic angle).

摘要

不同的研究者针对股骨头坏死不同治疗方法的预后,研究了各种人口统计学、实验室及影像学参数的影响。对52例(68髋)因股骨头Ficat和Arlet III期坏死而行髓芯减压术的患者进行了一项横断面研究。本研究的目的是评估各种影像学因素对髓芯减压术后疾病进展风险的预后意义。影像学参数包括Steinberg分期(III期或IV期)、大野分期(中央或外侧位置)、股骨头塌陷程度、新月征弧范围以及通过Kerboul联合坏死角测量的病变范围。患者的预后评估是在髓芯减压术后平均随访12年(范围4 - 18年)时进行。总体而言,68髋中有20髋(29%)预后良好。在44例Steinberg III期疾病的髋关节中,18髋(41%)接受了全髋关节置换术。相比之下,在Steinberg IV期髋关节中,24髋中有22髋(92%)接受了关节置换术。大野B期病变的生存率为50%(16髋中的8髋),而大野C期为23%(52髋中的12髋)。联合坏死角大于250度的髋关节生存率为16%(45髋中的7髋),而联合坏死角小于250度的髋关节生存率为57%(23髋中的13髋)。对于预后良好最佳的多元回归模型是Steinberg III期髋关节(无股骨头塌陷)、中央病变(大野B期)以及小病变(联合坏死角< 250度)。具备这种组合时,预后良好的比例为89%(9髋中的8髋)。相反,对于预后不良最佳的广义线性模型(14髋中无髋存活)是Steinberg IV期疾病(股骨头塌陷)、外侧位置(大野C期病变)以及病变范围大(联合坏死角> 250度)。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验