de Kerviler E, Leroy-Willig A, Clément O, Frija J
Service de Radiologie, Hôpital Saint-Louis, Paris.
Biomed Pharmacother. 1998;52(2):69-75. doi: 10.1016/S0753-3322(98)80006-1.
Due to short relaxation times, fat has a high signal on magnetic resonance images (MRI). This high signal, easily recognized on MRI, may be useful to characterize a lesion. However, small amounts of lipids are more difficult to detect on conventional MRI. In addition, the high signal due to fat may be responsible for artifacts such as ghosting and chemical shift. Lastly, a contrast enhancing tumor may be hidden by the surrounding fat. These problems have prompted development of fat suppression techniques in MRI. Fat may be suppressed on the basis of its difference in resonance frequency with water by means of frequency selective pulses or phase contrast techniques, or on the basis of its short T1 relaxation time by means of inversion recovery sequences. Lastly, hybrid techniques combining several of these fat suppression techniques are also possible. The aim of this paper is to review the basic principles of all these fat suppression techniques and to exemplify their clinical use.
由于弛豫时间短,脂肪在磁共振成像(MRI)上信号较高。这种在MRI上易于识别的高信号可能有助于对病变进行特征描述。然而,少量脂质在传统MRI上更难检测到。此外,脂肪产生的高信号可能会导致诸如鬼影和化学位移等伪影。最后,增强造影的肿瘤可能会被周围的脂肪掩盖。这些问题促使了MRI中脂肪抑制技术的发展。脂肪可以通过频率选择脉冲或相位对比技术,基于其与水的共振频率差异进行抑制,或者通过反转恢复序列,基于其短T1弛豫时间进行抑制。最后,结合这些脂肪抑制技术中的几种的混合技术也是可行的。本文的目的是回顾所有这些脂肪抑制技术的基本原理,并举例说明它们的临床应用。