Dodson W C, Moessner J, Miller J, Legro R S, Gnatuk C L
Division of Obstetrics and Gynecology, University Hospital, Penn State Geisinger Health System, Hershey, Pennsylvania, USA.
Fertil Steril. 1998 Sep;70(3):574-5. doi: 10.1016/s0015-0282(98)00210-6.
To compare the effectiveness of three methods of sperm preparation for IUI during superovulation of infertile women.
Randomized assignment of one of three sperm preparation methods.
University infertility practice.
PATIENT(S): Infertile couples undergoing superovulation and IUI.
INTERVENTION(S): The method of preparation of sperm for IUI during superovulation was assigned randomly to double centrifugation, multiple-tube swim-up, or Percoll density gradient.
MAIN OUTCOME MEASURE(S): Total number and percent recovery of motile sperm, percent of recovered sperm with normal morphology, and cycle fecundity.
RESULT(S): No method of sperm preparation provided better cycle fecundity than the others despite differences in sperm recovery.
CONCLUSION(S): Double centrifugation, multiple-tube swim-up, and Percoll density gradient sperm preparation for IUI yield similar cycle fecundity rates.
比较三种精子制备方法在不育女性超排卵期间用于宫腔内人工授精（IUI）的有效性。
随机分配三种精子制备方法之一。
大学不育症诊疗机构。
接受超排卵和IUI的不育夫妇。
超排卵期间用于IUI的精子制备方法被随机分配为双重离心法、多管上游法或Percoll密度梯度法。
活动精子的总数及回收率、形态正常的回收精子百分比以及周期受孕率。
尽管精子回收率存在差异，但没有一种精子制备方法的周期受孕率优于其他方法。
双重离心法、多管上游法和Percoll密度梯度法用于IUI的精子制备，其周期受孕率相似。
