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马耳他13 - 15岁学龄儿童的哮喘、鼻炎和湿疹——患病率、严重程度及相关因素[国际儿童哮喘和过敏研究(ISAAC)]

Asthma, rhinitis and eczema in Maltese 13-15 year-old schoolchildren -- prevalence, severity and associated factors [ISAAC]. International Study of Asthma and Allergies in Childhood.

作者信息

Montefort S, Lenicker H M, Caruna S, Agius Muscat H

机构信息

Department of Medicine, St. Luke's Hospital, Malta.

出版信息

Clin Exp Allergy. 1998 Sep;28(9):1089-99. doi: 10.1046/j.1365-2222.1998.00350.x.

Abstract

BACKGROUND

Allergic conditions, especially asthma, seem to be increasingly common the world over. The International Study of Asthma and Allergies in Childhood [ISAAC] was the first worldwide study carried out with standardized questionnaires in order to create a reliable global map of childhood allergy.

OBJECTIVES

The Maltese Islands were one of the centres participating in this study and in this paper the data obtained from 4184 13-15 year olds from 22 state and three private schools [88.7% response rate], and also data obtained from some added 'local' questions addressed to the same children, are included. in order to evaluate the problem of allergic conditions in Maltese schoolchildren.

RESULTS

27.9% of the participants were wheezers 'ever' while 16% were current wheezers. Of the latter children 15.1% were experiencing nocturnal wheezing at least once a week and 22% had a wheezing episode severe enough to limit speech. Nasal problems were present in 52.7% of these teenagers and 47.4% of all respondents persisted with these symptoms up to the year of answering the questionnaire. Hayfever had been diagnosed in 32.3% of all the children. 12.8% of respondents had a recurring itchy rash suggestive of eczema for at least 6 months of their lives and 10% had it currently. This was slightly lower than the global mean, unlike the case of wheezing, which in Malta was more common than the world average, and rhinitis, for which we had the second highest cumulative prevalence rate in the world. Multiple variables such as gender, smoking, family history of atopy, pets, soft furnishings and living in busy roads affected the prevalence and severity of the allergic conditions studied.

CONCLUSIONS

Allergic conditions are very common in Maltese schoolchildren and are causing a lot of hardship to these same youngsters. The results of this study should serve as a stimulus to try and decrease this suffering through better management of these conditions, measures to control possible detrimental factors and further research on asthma, allergic rhinitis and eczema.

摘要

背景

过敏症,尤其是哮喘,在全球似乎越来越普遍。儿童哮喘和过敏国际研究(ISAAC)是首次在全球范围内使用标准化问卷进行的研究,旨在绘制出可靠的儿童过敏全球地图。

目的

马耳他群岛是参与该研究的中心之一。本文纳入了从22所公立学校和3所私立学校的4184名13 - 15岁学生中获得的数据(回复率为88.7%),以及针对这些学生提出的一些补充“本地”问题所获得的数据,以评估马耳他学童的过敏症问题。

结果

27.9%的参与者“曾经”有过喘息,16%为当前喘息者。在后者中,15.1%的儿童每周至少有一次夜间喘息,22%有严重到足以影响说话的喘息发作。52.7%的青少年有鼻部问题,47.4%的所有受访者在回答问卷当年仍有这些症状。32.3%的儿童被诊断为花粉热。12.8%的受访者有反复出现的瘙痒性皮疹,提示湿疹,且在其生命中至少持续6个月,10%目前仍有。这略低于全球平均水平,与喘息情况不同,喘息在马耳他比世界平均水平更常见,鼻炎方面,马耳他的累积患病率在世界上排名第二。性别、吸烟、特应性家族史、宠物、软家具以及居住在繁忙道路附近等多个变量影响了所研究的过敏症的患病率和严重程度。

结论

过敏症在马耳他学童中非常普遍,给这些青少年带来了很多痛苦。本研究结果应促使人们努力通过更好地管理这些病症、控制可能的有害因素以及对哮喘、过敏性鼻炎和湿疹进行进一步研究来减轻这种痛苦。

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