与链球菌感染相关的复发性皮肤结节性多动脉炎。
Relapsing cutaneous polyarteritis nodosa associated with streptococcal infections.
作者信息
Albornoz M A, Benedetto A V, Korman M, McFall S, Tourtellotte C D, Myers A R
机构信息
Department of Internal Medicine, Mercy Catholic Medical Center, Darby, Pennsylvania, USA.
出版信息
Int J Dermatol. 1998 Sep;37(9):664-6. doi: 10.1046/j.1365-4362.1998.00493.x.
BACKGROUND
Polyarteritis nodosa is an aggressive, often fatal form of vasculitis associated with multi-organ involvement. Cutaneous polyarteritis nodosa is purported to be a more benign form of this disorder with involvement limited to the skin.
METHODS
The identification of a female patient from childhood to adulthood documenting repeated episodes of cutaneous polyarteritis nodosa following bouts of recurrent streptococcal pharyngitis.
RESULTS
Repeated bouts of streptococcal pharyngitis at ages 11, 28, and 33 years were followed by episodes of cutaneous polyarteritis nodosa, documented by histopathologic skin changes and clinical presentation, and confirmed by therapeutic management.
CONCLUSIONS
Various infectious and non-infectious conditions have been linked both to the initiation and relapse of this disease. We describe a patient with recurrent episodes of cutaneous polyarteritis nodosa spanning a period of over 20 years with each episode appearing to be linked to a prior streptococcal infection.
背景
结节性多动脉炎是一种侵袭性、通常致命的血管炎形式，与多器官受累有关。皮肤型结节性多动脉炎据称是这种疾病的一种较为良性的形式，受累仅限于皮肤。
方法
鉴定一名从儿童期到成年期的女性患者，记录其在复发性链球菌性咽炎发作后反复出现皮肤型结节性多动脉炎的情况。
结果
在11岁、28岁和33岁时反复发生链球菌性咽炎，随后出现皮肤型结节性多动脉炎发作，经组织病理学皮肤改变和临床表现记录，并通过治疗管理得到证实。
结论
各种感染性和非感染性疾病都与这种疾病的发病和复发有关。我们描述了一名患者，其皮肤型结节性多动脉炎反复发作超过20年，每次发作似乎都与先前的链球菌感染有关。
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