与胶原蛋白合成相关的肽结合羟赖氨酸和大的多肽。
Peptide-bound hydroxylysine and large polypeptides related to collagen synthesis.
作者信息
Askenasi R, Rao V H, Devos A
出版信息
Eur J Clin Invest. 1976 Sep 10;6(5):361-3. doi: 10.1111/j.1365-2362.1976.tb00529.x.
Abstract
About 10% of the urinary hydroxylysine is linked to peptides. There is no significant difference between the excretion of peptide-bound hydroxylysine and hydroxylysine measured in the non-dialysable fraction of the urine. Non-dialysable hydroxylysine is highly glycosylated and contains mainly glucosyl-galactosyl-hydroxylysine. It is concluded that the urinary peptide-bound hydroxylysine is present in the non-dialysable collagen polypeptides. Their unusual carbohydrate composition is discussed.
摘要
约10%的尿羟赖氨酸与肽相连。结合肽的羟赖氨酸排泄量与尿中不可透析部分测得的羟赖氨酸排泄量之间无显著差异。不可透析的羟赖氨酸高度糖基化，主要含有葡萄糖基-半乳糖基-羟赖氨酸。得出的结论是，尿中结合肽的羟赖氨酸存在于不可透析的胶原蛋白多肽中。并讨论了它们不同寻常的碳水化合物组成。
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引用本文的文献
1
The origin of urinary hydroxylysyl glycosides in Paget's disease of bone and in primary hyperparathyroidism.骨佩吉特病和原发性甲状旁腺功能亢进症中尿羟赖氨酸糖苷的来源。
Calcif Tissue Res. 1976 Nov 24;22(1):35-40. doi: 10.1007/BF02010344.
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