Wieshmann U C, Barker G J, Symms M R, Bartlett P A, Stevens J M, Shorvon S D
Epilepsy Research Group, Institute of Neurology, London, UK.
Neuroradiology. 1998 Aug;40(8):483-9. doi: 10.1007/s002340050630.
We developed a 3D version of fast fluid-attenuated inversion-recovery imaging (FLAIR) which provides images with a slice thickness of 1.5 mm. We present our initial experience with 3D fast FLAIR in patients with epilepsy. We compared 3D fast FLAIR (slice thickness 1.5 mm), 2D fast FLAIR (slice thickness 5 mm) and a 3D spoiled GRASS (IRSPGR) sequence (slice thickness 1.5 mm) in 10 patients with lesional epilepsy (head injury 1, hippocampal sclerosis 2, low-grade glioma 2, dysembryoplastic neuroepithelial tumour 2, polymicrogyria 1, perinatal infarct 1 and presumed thrombosed aneurysm 1). Both 2D and 3D fast FLAIR sequences yielded higher conspicuity for lesions than the T1-weighted IRSPGR sequence, except in the patient with polymicrogyria. The extent of the lesion, in particular that of low-grade tumours, was best assessed on 3D fast FLAIR images. 3D fast FLAIR may be a useful additional tool especially for imaging low-grade tumours.
我们开发了一种三维快速液体衰减反转恢复成像(FLAIR),其提供层厚为1.5毫米的图像。我们展示了在癫痫患者中使用三维快速FLAIR的初步经验。我们对10例有病灶性癫痫的患者(头部损伤1例、海马硬化2例、低级别胶质瘤2例、胚胎发育不良性神经上皮肿瘤2例、多小脑回1例、围产期梗死1例、推测为血栓形成的动脉瘤1例)进行了三维快速FLAIR(层厚1.5毫米)、二维快速FLAIR(层厚5毫米)和三维扰相梯度回波(IRSPGR)序列(层厚1.5毫米)的比较。除多小脑回患者外,二维和三维快速FLAIR序列对病灶的显示均比T1加权IRSPGR序列更清晰。在三维快速FLAIR图像上对病灶范围,尤其是低级别肿瘤的范围评估最佳。三维快速FLAIR可能是一种有用的辅助工具,特别是用于低级别肿瘤的成像。