Rydberg J N, Hammond C A, Grimm R C, Erickson B J, Jack C R, Huston J, Riederer S J
Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905.
Radiology. 1994 Oct;193(1):173-80. doi: 10.1148/radiology.193.1.8090888.
To evaluate fast fluid-attenuated inversion-recovery (FLAIR) technique for imaging brain abnormalities.
A fast FLAIR sequence was developed that provided 36 5-mm contiguous sections in 5 minutes 8 seconds. Resulting images were compared with dual-echo T2-weighted spin-echo images of 41 consecutive patients with brain abnormalities.
Contrast and contrast-to-noise ratios (C/Ns) (for contrast between the lesion and background and between the lesion and cerebrospinal fluid) for fast FLAIR exceeded the corresponding values for T2-weighted spin-echo images for all but the second-echo lesion-to-background C/N. Fast FLAIR provided equivalent or greater overall lesion conspicuity and enabled greater lesion detection in 98% and 100%, respectively, of the evaluations. Fast FLAIR images more often had image artifact, but this did not interfere with image interpretation in a significantly (P < or = .05) greater number of evaluations.
Fast FLAIR provides images that are superior to proton-density- and T2-weighted images for many image quality criteria.
评估快速液体衰减反转恢复（FLAIR）技术对脑部异常的成像效果。
开发了一种快速FLAIR序列，该序列在5分8秒内可提供36个5毫米连续层面的图像。将所得图像与41例连续脑部异常患者的双回波T2加权自旋回波图像进行比较。
除第二次回波的病变与背景对比度噪声比（C/N）外，快速FLAIR的对比度及病变与背景之间、病变与脑脊液之间的对比度噪声比均超过T2加权自旋回波图像的相应值。在98%和100%的评估中，快速FLAIR分别提供了相当或更高的整体病变清晰度，且能检测到更多病变。快速FLAIR图像更常出现图像伪影，但在显著更多（P≤0.05）的评估中，这并未干扰图像解读。
对于许多图像质量标准而言，快速FLAIR提供的图像优于质子密度加权和T2加权图像。
