Hansen L H, Lund C
Herning Centralsygehus, medicinsk afdeling.
Ugeskr Laeger. 1998 Sep 14;160(38):5514-5.
Entamoeba histolytica is a very uncommon etiology of travelers diarrhoea, but may be an important differential diagnosis to inflammatory bowel disease. A misdiagnosis of amoebic colitis as inflammatory bowel disease followed by inadvertent treatment with corticosteroids may be fatal. Current techniques for the diagnosis of amoebiasis include stool studies, endoscopic biopsy and serology. Demonstration of haematophagous trophozoites in feces or in tissue biopsy is the definitive method for diagnosis. Unfortunately both methods have many drawbacks. If the specimens are negative, serology can support the diagnosis especially in a non-endemic area where a positive test is highly predictive of current disease.
溶组织内阿米巴是旅行者腹泻非常罕见的病因,但可能是炎性肠病的重要鉴别诊断。将阿米巴结肠炎误诊为炎性肠病,随后不慎使用皮质类固醇治疗可能会致命。目前诊断阿米巴病的技术包括粪便检查、内镜活检和血清学检查。在粪便或组织活检中发现噬血细胞滋养体是确诊的方法。不幸的是,这两种方法都有许多缺点。如果标本为阴性,血清学检查可辅助诊断,尤其是在非流行地区,阳性检测结果对当前疾病具有高度预测性。