莫斯塔尔大学临床医院炎症性肠病中阿米巴病的患病率
Prevalence of amebiasis in inflammatory bowel disease in University Clinical Hospital Mostar.
作者信息
Babić Emil, Bevanda Milenko, Mimica Mladen, Karin Maja, Volarić Mile, Bogut Ante, Barišić Tatjana, Pravdić Danijel, Šutalo Nikica
机构信息
Department of Gastroenterology and Hepatology, University of Mostar Clinical Hospital, Bijeli Brijeg bb, 88000 Mostar, Bosnia and Herzegovina.
Department of Ginecology, University of Mostar Clinical Hospital, Bijeli Brijeg bb, 88000 Mostar, Bosnia and Herzegovina.
出版信息
Springerplus. 2016 Sep 15;5(1):1586. doi: 10.1186/s40064-016-3261-7. eCollection 2016.
AIM
To explore the prevalence of amebiasis in inflammatory bowel disease (IBD), Crohn's disease and ulcerative colitis, in patients in Clinical hospital Mostar (Bosnia and Herzegovina, region of Herzegovina).
METHODS
In this study, Entamoeba histolytica/dispar prevalence was investigated in fresh faeces by native microscopy and immunochromatographic rapid assay "RIDA(®)QUICK Entamoeba test", in 119 cases of new found IBD patients, 84 of ulcerative colitis and 35 of Crohn's disease and in control group who had also 119 patients who didn't have any gastrointestinal complaints. IBD diagnosis was established by standard diagnostic procedures (anamnesis, clinical manifestations, laboratory, endoscopy and biopsy).
RESULTS
Entamoeba histolytica/dispar were found in 19 (16.0 %) of a total of 119 cases, 12 (14.3 %) of the 84 patients with ulcerative colitis and 7 (20.0 %) of the 35 patients with Crohn's disease. As for the 119 patients in the control group who had not any gastrointestinal complaints, 2 (1.7 %) patients were found to have E. histolytica/dispar in their faeces. Amoeba prevalence in the patient group was determined to be significantly higher in group with Crohn's disease, ulcerative colitis and IBD total than in the control group (p < 0.001).
CONCLUSION
Ameba infections in patients with Crohn's disease and ulcerative colitis, have a greater prevalence compared to the normal population.
目的
探讨波斯尼亚和黑塞哥维那黑塞哥维那地区莫斯塔尔临床医院炎症性肠病（IBD）、克罗恩病和溃疡性结肠炎患者中阿米巴病的患病率。
方法
在本研究中，采用活体显微镜检查和免疫层析快速检测“RIDA(®)QUICK 溶组织内阿米巴检测”，对119例新确诊的IBD患者、84例溃疡性结肠炎患者、35例克罗恩病患者以及119例无任何胃肠道不适的对照组患者的新鲜粪便进行溶组织内阿米巴/迪斯帕内阿米巴患病率调查。IBD诊断通过标准诊断程序（病史、临床表现、实验室检查、内镜检查和活检）确定。
结果
在119例患者中，共19例（16.0%）检测到溶组织内阿米巴/迪斯帕内阿米巴，其中84例溃疡性结肠炎患者中有12例（14.3%），35例克罗恩病患者中有7例（20.0%）。在119例无任何胃肠道不适的对照组患者中，2例（1.7%）粪便中检测到溶组织内阿米巴/迪斯帕内阿米巴。克罗恩病组、溃疡性结肠炎组和IBD总患者组的阿米巴患病率显著高于对照组（p < 0.001）。
结论
与正常人群相比，克罗恩病和溃疡性结肠炎患者的阿米巴感染患病率更高。
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