幽门螺杆菌感染中的细菌因素与免疫发病机制
Bacterial factors and immune pathogenesis in Helicobacter pylori infection.
作者信息
Shimoyama T, Crabtree J E
机构信息
First Department of Internal Medicine, Hirosaki University School of Medicine, Japan.
出版信息
Gut. 1998 Jul;43 Suppl 1(Suppl 1):S2-5.
Abstract
Virulent Helicobacter pylori strains which have been clinically associated with severe outcome induce increased gastric mucosal immune responses. Although several bacterial pathogenic factors have been shown to have a considerable role in H pylori infection, variability in host immune responses may also contribute to mucosal damage in H pylori associated gastritis.
摘要
临床上与严重后果相关的毒力幽门螺杆菌菌株会诱导胃黏膜免疫反应增强。尽管已表明几种细菌致病因素在幽门螺杆菌感染中起重要作用，但宿主免疫反应的变异性也可能导致幽门螺杆菌相关性胃炎的黏膜损伤。
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本文引用的文献
1
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Mol Microbiol. 1998 Apr;28(1):37-53. doi: 10.1046/j.1365-2958.1998.00770.x.
2
Decrease in gastric permeability to sucrose following cure of Helicobacter pylori infection.幽门螺杆菌感染治愈后胃对蔗糖的通透性降低。
Helicobacter. 1997 Mar;2(1):44-7. doi: 10.1111/j.1523-5378.1997.tb00057.x.
3
Differential stimulation of interleukin-12 (IL-12) and IL-10 by live and killed Helicobacter pylori in vitro and association of IL-12 production with gamma interferon-producing T cells in the human gastric mucosa.活的和灭活的幽门螺杆菌在体外对白细胞介素-12（IL-12）和IL-10的差异刺激以及人胃黏膜中IL-12产生与产生γ干扰素的T细胞的关联
Infect Immun. 1997 Oct;65(10):4229-35. doi: 10.1128/iai.65.10.4229-4235.1997.
4
Different cytokine profile and antigen-specificity repertoire in Helicobacter pylori-specific T cell clones from the antrum of chronic gastritis patients with or without peptic ulcer.患有或不患有消化性溃疡的慢性胃炎患者胃窦部幽门螺杆菌特异性T细胞克隆中不同的细胞因子谱和抗原特异性库。
Eur J Immunol. 1997 Jul;27(7):1751-5. doi: 10.1002/eji.1830270723.
5
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Gut. 1997 Jun;40(6):739-44. doi: 10.1136/gut.40.6.739.
6
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J Clin Invest. 1997 Apr 1;99(7):1628-36. doi: 10.1172/JCI119325.
10
Epithelium related deposition of activated complement in Helicobacter pylori associated gastritis.幽门螺杆菌相关性胃炎中活化补体的上皮相关沉积
Gut. 1997 Feb;40(2):196-203. doi: 10.1136/gut.40.2.196.
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